Results 71 to 80 of about 1,031,287 (257)

Application of Bovine Nasal Epithelial Cells as an In Vitro Model for Studying Viral Infection in the Upper Respiratory Tract

Viruses
Bovine respiratory disease complex (BRDC) is a multifactorial and globally prevalent condition involving a combination of viral and bacterial pathogens, as well as environmental stressors.
Malte Pitters, Henrik Fritsch, Ang Su, Klaus Jung, Paul Becher   +4 more
doaj   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source

Immunology of Bovine Pestivirus Infection

, 1996
The bovine pestiviruses (here referred to as bovine viral diarrhea viruses-BVDV) cause three types of disease: bovine viral diarrhea (BVD), mucosal disease (MD) or fetal disease (FD).
Reddy, Sudhir K., Frossard, J. P., Minocha, Harish, McVey, D. Scott   +3 more
core   +1 more source

A multiplex real-time fluorescence-based quantitative PCR assay for calf diarrhea viruses

Frontiers in Microbiology
IntroductionCalf diarrhea is a significant condition that has a strong effect on the cattle industry, resulting in huge economic losses annually. Bovine torovirus (BToV), bovine enterovirus (BEV), bovine norovirus (BNoV), bovine coronavirus (BCoV ...
Wenxin Meng, Wenxin Meng, Zihan Chen, Zihan Chen, Qifeng Jiang, Qifeng Jiang, Jinping Chen, Jinping Chen, Xiaoying Guo, Xiaoying Guo, Zihang Ma, Zihang Ma, Kun Jia, Kun Jia, Shoujun Li, Shoujun Li   +15 more
doaj   +1 more source

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

Advanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu, Qibo Li, Weihao Zhang, Guan Zheng, Junhua Chen, Yipeng Zeng, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Jiajie Lin, Zepeng Su, Zhongyu Xie   +12 more
wiley   +1 more source

Diabetes Mellitus in Cattle Infected With Bovine Viral Diarrhea Mucosal Disease Virus

, 1992
Diabetes in cattle has various etiologies1. In humans, virus-induced insulin dependent diabetes mellitus (IDDM) has been reported. It has also been reported that cattle infected with foot-and-mouth disease contracted diabetes mellitus2.
Hagiwara, K., Takahashi, K., Tajima, M., Yazawa, T.   +3 more
core   +1 more source

Enzyme-linked immunosorbent assay using a virus type-specific peptide based on a subdomain of envelope protein e(rns) for serologic diagnosis of pestivirus infections in swine [PDF]

, 2001
Peptides deduced from the C-terminal end (residues 191 to 227) of pestivirus envelope protein Erns were used to develop enzyme-linked immunosorbent assays (ELISAs) to measure specifically antibodies against different types of pestiviruses.
Langedijk, J.P., Smit, J.A., de, Meloen, R.H., Middel, W.G., Kramps, J.A., de Smit, J.A.   +5 more
core   +1 more source

Influenza Viral Manipulation of Sphingolipid Metabolism and Signaling to Modulate Host Defense System

Scientifica, 2014
Viruses attempt to create a distinctive cellular environment to favor viral replication and spread. Recent studies uncovered new functions of the sphingolipid signaling/metabolism during pathogenic virus infections.
Madhuvanthi Vijayan, Bumsuk Hahm
doaj   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Diverse outcomes of bovine viral diarrhea virus (BVDV) infections in a herd naturally infected during pregnancy: A case study

, 2014
A beef producer purchased pregnant Angus crossbred cows with nursing calves. The purchased cattle, their nursing calves, and subsequent born calves were not initially tested for bovine viral diarrhea virus (BVDV), nor was there a history of vaccination ...
Ridpath, Julia F., Rezabek, Grant B., Grant, Ryan, Burge, Lurinda J., Fulton, Robert W.   +4 more
core   +1 more source