Results 31 to 40 of about 1,327 (175)

Diarylheptanoids of with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells

Natural Product Communications, 2015
Eight new diarylheptanoids, a 1.2:1 mixture of (3S )- and (3 R )-1-(4-hydroxyphenyl)-7-phenyl-(4 E ,6 E )-4,6-heptadien-3-ol ( 1a and 1b ), a racemic mixture of (3S )- and (3 R )-1-(4-hydroxyphenyl)-3-methoxy-7-phenyl-(4 E ,6 E )-4,6-heptadiene ( 2a and ...
Nilubon Sornkaew, Yuan Lin, Fei Wang, Guolin Zhang, Ratchanaporn Chokchaisiri, Ailian Zhang, Kanjana Wongkrajang, Parichat Suebsakwong, Pawinee Piyachaturawat, Apichart Suksamrarn   +9 more
doaj   +1 more source

Gingerol Synergizes the Cytotoxic Effects of Doxorubicin against Liver Cancer Cells and Protects from Its Vascular Toxicity

Molecules, 2016
Hydroxyphenylalkanes and diarylheptanoids possess potential therapeutic value in different pathophysiological conditions, such as malignancy. In the current study, naturally isolated hydroxyphenylalkane and diarylheptanoid compounds were investigated for
Fahad A. Al-Abbasi, Eman A. Alghamdi, Mohammed A. Baghdadi, Abdulmohsin J. Alamoudi, Ali M. El-Halawany, Hany M. El-Bassossy, Ali H. Aseeri, Ahmed M. Al-Abd   +7 more
doaj   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

Food Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du, Yifan Zhao, Li Dong, Chen Ma, Xiaosong Hu, Daotong Li, Fang Chen, Yinghua Luo   +7 more
wiley   +1 more source

Different Accumulation Profiles of Multiple Components Between Pericarp and Seed of Alpinia oxyphylla Capsular Fruit as Determined by UFLC-MS/MS

Molecules, 2014
Plant secondary metabolites are known to not only play a key role in the adaptation of plants to their environment, but also represent an important source of active pharmaceuticals.
Feng Chen, Hai-Long Li, Yin-Feng Tan, Wei-Wei Guan, Jun-Qing Zhang, Yong-Hui Li, Yuan-Sheng Zhao, Zhen-Miao Qin   +7 more
doaj   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

CURCUMINA, O PÓ DOURADO DO AÇAFRÃO-DA-TERRA: INTROSPECÇÕES SOBRE QUÍMICA E ATIVIDADES BIOLÓGICAS

Química Nova, 2015
Turmeric, obtained from the dried rhizomes of Curcuma longa (Zingiberaceae), is a golden colored material, commonly used around the world for seasoning and coloring food dishes.
Vitor Sueth-Santiago, Gustavo Peron Mendes-Silva, Débora Decoté-Ricardo, Marco Edilson Freire de Lima   +3 more
doaj   +1 more source

Protective Effect of Alpinia oxyphylla Fruit against tert-Butyl Hydroperoxide-Induced Toxicity in HepG2 Cells via Nrf2 Activation and Free Radical Scavenging and Its Active Molecules

Antioxidants, 2022
Alpinia oxyphylla Miq. (Zingiberaceae) extract exerts protective activity against tert-butyl hydroperoxide-induced toxicity in HepG2 cells, and the antioxidant response element (ARE) luciferase activity increased 6-fold at 30 μg/mL in HepG2 cells ...
Chae Lee Park, Ji Hoon Kim, Je-Seung Jeon, Ju-hee Lee, Kaixuan Zhang, Shuo Guo, Do-hyun Lee, Eun Mei Gao, Rak Ho Son, Young-Mi Kim, Gyu Hwan Park, Chul Young Kim   +11 more
doaj   +1 more source

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

Biological Evaluation of Curcumin and Related Diarylheptanoids

Zeitschrift für Naturforschung C, 2006
Abstract Nine derivatives of three natural diarylheptanoids, curcumin, demethoxycurcumin and bisdemethoxycurcumin, were prepared. Their antioxidant, free radical scavenging, nitric oxide (NO) inhibitory and cytotoxic activities were evaluated and compared with those of the respective natural compounds. Curcumin (1), demethoxycurcumin (2),
Faridah, Abas, Lim Siang, Hui, Syahida, Ahmad, Johnson, Stanslas, D A, Israf, Khozirah, Shaari, Nordin H, Lajis   +6 more
openaire   +2 more sources

Gingerenone A attenuates gastric cancer progression via PI3K/Akt/FOXO1 signaling pathway, autophagy, and apoptosis

Asian Pacific Journal of Tropical Biomedicine
Objective: To investigate anti-gastric cancer effects of gingerenone A (GA) and explore its association with the PI3K/Akt/FOXO1 signaling pathway, autophagy, and apoptosis. Methods: Cell viabilities were detected via CCK-8 assay. Proliferation, migration,
Yang Zhou, Rui Mu, Tong Wu, Xiao-Hui Mu, Hui Wan, Liang-Yu Zhao   +5 more
doaj   +1 more source