Results 41 to 50 of about 1,327 (175)

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

Phytotherapy Research, Volume 40, Issue 7, Page 4041-4055, July 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

Kaempferide in Alpinia officinarum Hance Exerts Anti‐Hepatocellular Carcinoma Activity by Inhibiting Mitophagy Through Downregulation of BNIP3L

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Hepatocellular carcinoma (HCC), the most common primary malignant tumour of the liver, is notorious for its high mortality rate.Alpinia officinarum Hance (A. officinarum) is a perennial medicinal herb used for the management of abdominal pain, vomiting, and gastrointestinal tumours, and is widely applied as a dietary intervention by the Li ...
Lu Lu, Changxian Li, Cunzhen Jiang, Yuan Zhao, Yinghong Zhong, Jicheng Hu, Zhe Wang, Mingyan Zhou, Jian Xu, Xiangcheng Li   +9 more
wiley   +1 more source

Diarylheptanoid 7-(3,4-Dihydroxyphenyl)-5- Hydroxy-1-Phenyl- (1E)-1-Heptene from Curcuma Comosa Roxb. Inhibits Nucleophosmin Localization and Induces Apoptosis in KG-1a Leukemic Stem Cells

Journal of Health Science and Medical Research (JHSMR)
Objective: This study aimed to investigate the effect of the diarylheptanoid 7-(3,4-dihydroxyphenyl)-5- hydroxy-1-phenyl-(1E)-1-heptene (DDHPH) from the rhizome of Curcuma comosa Roxb.
Natsima Viriyaadhammaa, Suwit Duangmano, Pawaret Panyajai, Khin Khin Gyi, Singkome Tima, Sawitree Chiampanichayakul, Siriporn Okonogi, Pornngarm Dejkriengkraikul, Jeffrey Krise, Aroonchai Saiai, Songyot Anuchapreeda   +10 more
doaj   +1 more source

Activation of JNK and p38 in MCF-7 Cells and the In Vitro Anticancer Activity of Alnus hirsuta Extract

Molecules, 2020
JNK and p38 are important mitogen-activated protein kinases (MAPKs) that respond to stress stimuli. The stress-activated MAPKs associated with apoptotic cell death play vital roles in mammalian cells.
Mina Ryu, Chung Ki Sung, Young Jun Im, ChangJu Chun   +3 more
doaj   +1 more source

Enhanced CO2 Coordinates the Spatial Recruitment of Diazotrophs in Rice Via Root Development

Plant, Cell &Environment, Volume 49, Issue 7, Page 3678-3693, July 2026.
ABSTRACT Understanding the reciprocal interaction between root development and coadapted beneficial microbes in response to elevated CO2 (eCO2) will facilitate the identification of nutrient‐efficient cultivars for sustainable agriculture. Here, systematic morphological, anatomical, chemical and gene expression assays performed under low‐nitrogen ...
Junwen Zhao, Yuting Chen, Qi Tao, Lukas Schreiber, Kiran Suresh, Michael Frei, Muhammad Shahedul Alam, Bing Li, Yaping Zhou, Marcel Baer, Frank Hochholdinger, Changquan Wang, Peng Yu   +12 more
wiley   +1 more source

Preparative Purification of Anti-Proliferative Diarylheptanoids from Betula platyphylla by High-Speed Counter-Current Chromatography

Molecules, 2016
A simple and rapid method using high-speed counter-current chromatography (HSCCC), along with bioassay-guided fractionation based on the anti-proliferative activity against renal and colon cancer cells, has been developed for the preparative separation ...
Namki Cho, Hyun Woo Kim, Tae Bum Kim, Tanya T. Ransom, John A. Beutler, Sang Hyun Sung   +5 more
doaj   +1 more source

Mechanochemical Hydrodeoxygenations

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
A silver‐catalyzed mechanochemical hydrodeoxygenation with triethylsilane as reductant allows to convert ketones to the corresponding methylene derivatives in good yields after a short reaction time. Selected examples show that also alcohols, ethers, and sulfoxides can react. In this work, a mechanochemical hydrodeoxygenation (HDO) was developed. Using
Lena M. Hanek, Carsten Bolm
wiley   +1 more source

Foodborne Carcinogens: Formation Pathways, Health Risks, and Cutting‐Edge Physical and Chemical Prevention Strategies

eFood, Volume 7, Issue 3, June 2026.
This review highlights the formation of foodborne carcinogens during processing and evaluates different mitigation strategies, including natural antioxidants and modern cooking techniques, to reduce associated cancer risks and enhance food safety. ABSTRACT Food processing methods, though vital for improving food safety, taste, and shelf life, can ...
Naglaa S. Ashmawy, Ahmed A. Zaky, Noha H. Badr, Ali Korin, Mohamed A. Farag   +4 more
wiley   +1 more source

ETLINGERA GENUS: PHYTOCHEMICAL SCREENING AND ANTICANCER ACTIVITY

Jurnal Farmasi Sains dan Praktis, 2022
Etlingera is one of the plant genera from the Zingiberaceae family and is widely distributed in Asia to the Pacific Islands, with various species ranging from 150 to 200 species.
Wahyuni -, Ajeng Diantini, Mohammad Ghozali, Sahidin I   +3 more
doaj   +1 more source

Analysis of Quality Differences in Rhizoma Musae From Different Origins Based on Rhizosphere Soil Bacterial Diversity and Metabolomics

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study integrated bacterial diversity and metabolomics to explore correlations among soil factors, rhizosphere microorganisms, and quality of Rhizoma Musae from different origins. Significant differences in active components and 571 differential metabolites were detected, enriched in key secondary metabolism pathways.
Jian Zhang, Xinying Xiong, Jing Lei, Yu Zhang, Yae Yang, Zhongze Wang, Wanyan Shen, Xuegang Luo, Fanzhi Liu, Xiaorong Zhao, Xiaoyu Yang, Peiling Long, Jiandong Liu   +12 more
wiley   +1 more source