Results 231 to 240 of about 83,038 (344)

Synthesis of Trifluoromethylated Analogues of the Cyclic Lipopeptide Iturin A and Evaluation of their Antifungal Activity

open access: yesChemPlusChem, Volume 91, Issue 1, January 2026.
Iturin A is an antifungal lipopeptide with broad applications. Here, we present a novel synthesis and semisynthesis of trifluoromethylated iturin A analogues. Their antifungal activity was evaluated against Fusarium graminearum and Candida albicans.
Periklis Karamanis   +5 more
wiley   +1 more source

Isomerization of α‐Pinene Oxide to Trans‐Pinocarveol

open access: yesHelvetica Chimica Acta, Volume 109, Issue 1, January 2026.
An operationally simple protocol for the selective isomerization of α‐pinene oxide (APO) to trans‐pinocarveol (TPC) is disclosed, which leverages inexpensive pyridinium‐halide organocatalysts to mitigate competing 1,2‐alkyl shifts. The scalability of this methodology is demonstrated on a decagram scale and catalyst‐recycling is validated through the ...
Emanuel Studer   +2 more
wiley   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

open access: yesChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten   +5 more
wiley   +1 more source

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