Sedative Effects of Intraperitoneal Diazepam in Mice
Objectives: To determine the effectiveness of Diazepam in comparison with Phenobarbital. Methods: Twenty-seven male Swiss Webster mice were used and randomly divided into three groups of negative control (NS), positive control (Phenobarbital), and ...
Marsha Vania+3 more
doaj
Trends in long-term prescribing of dependence forming medicines [PDF]
Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
McManus, S.+3 more
core
Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy [PDF]
Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease.
A Klang+58 more
core +2 more sources
Diazepam in pulmonary surgery [PDF]
Diazepam compared to thiopentone gives a greatly improved intravenous induction; it is thus a new and important pharmacological contribution in our search for an ideal anaesthetic technique for pulmonary surgery.
Roland Desrosiers, Jean-Paul Dechêne
openaire +3 more sources
Anxiety as a Factor in the Development of Autistic Spectrum Symptoms: an Experimental Study [PDF]
It is well known that psychoemotional disorders may be accompanied by decreased sociability in humans. It has been shown that repeated social defeats in 10 daily agonistic interactions in male mice led to development of the expressed level of anxiety and to reduction of communication estimated in the elevated plus-maze and partition tests, respectively.
arxiv
Sedation for Gastrointestinal Endoscopic Procedures in the Elderly: Getting Safer but Still Not Nearly Safe Enough [PDF]
Previously published UK reports showed that excessively large doses of benzodiazepines and opiates were being commonly used to sedate elderly patients for gastrointestinal (GI) endoscopy. This unsafe practice has lead to avoidable morbidity and mortality.
Bell, G. D.+8 more
core
Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels [PDF]
Recent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy
Klugbauer, Norbert+5 more
core +4 more sources
Diazepam induced oxidative DNA damage in cultured human lymphocytes
Diazepam is a benzodiazepine compound that is mainly used for anxiety, muscle spasms, seizures and insomnia. Several studies have shown that long-term Diazepam treatment is associated with oxidative stress. In this study, the possible genotoxic effect of
Mohammad Azab+3 more
doaj
The ethyl acetate fraction of Quercus incana yielded two new compounds [1 and 2]. The characterization and structure elucidation of these compounds were carried out through various spectroscopic techniques such as mass spectrometry along with one- and ...
Rizwana Sarwar+10 more
doaj +1 more source
Effects of filtration sterilization on the stability of ketamine, selected benzodiazepines and metabolites in female urine [PDF]
Benzodiazepines (Benzos) and ketamine (K) are compounds that have been encountered in Drug-Facilitated Sexual Assault (DFSA) cases. Due to the intimate nature of these crimes, evidence collection is often postponed due to delays and/or reluctance in ...
Zhen, Lin
core +1 more source