Results 21 to 30 of about 342 (137)

Study of Drug Delivery Behavior Through Biomembranes Using Thermal and Bioanalytical Techniques [PDF]

, 2010
This Master of Science thesis encompasses two projects in chemical pharmaceuticals. The first is a study of excipients and the added new information collected beyond Thermal Gravimetric Analysis and Differential Scanning Calorimetry from Dielectric ...
Venumuddala, Hareesha Reddy
core   +2 more sources

Management of Psychosis in Parkinson’s Disease: Emphasizing Clinical Subtypes and Pathophysiological Mechanisms of the Condition

Parkinson's Disease, Volume 2017, Issue 1, 2017., 2017
Investigation into neuropsychiatric symptoms in Parkinson’s disease (PD) is sparse and current drug development is mainly focused on the motor aspect of PD. The tight association of psychosis with an impaired quality of life in PD, together with an important underreporting of this comorbid condition, contributes to its actual insufficient assessment ...
Raquel N. Taddei, Seyda Cankaya, Sandeep Dhaliwal, K. Ray Chaudhuri, Giovanni Mirabella   +4 more
wiley   +1 more source

Freeze Dried Quetiapine‐Nicotinamide Binary Solid Dispersions: A New Strategy for Improving Physicochemical Properties and Ex Vivo Diffusion

Journal of Pharmaceutics, Volume 2016, Issue 1, 2016., 2016
Improving the physicochemical properties and oral bioavailability of quetiapine fumarate (QF) enabling enhanced antipsychotic attributes are the main aims of this research. The freeze dried solid dispersion strategy was adopted using nicotinamide (NIC) as highly soluble coformer.
Ahmed Mahmoud Abdelhaleem Ali, Mayyas Mohammad Ahmad Al-Remawi, Sanyog Jain   +2 more
wiley   +1 more source

Effects of Green Tea Extracts on the Pharmacokinetics of Quetiapine in Rats

Evidence-Based Complementary and Alternative Medicine, Volume 2015, Issue 1, 2015., 2015
Quetiapine is an atypical antipsychotic, used clinically in the treatment of schizophrenia, acute mania in bipolar disorders, and bipolar depression in adults. In this study, the effect of green tea extracts (GTE) on the pharmacokinetics of quetiapine (substrate of CYP3A4) was investigated in rats.
Essam Ezzeldin, Yousif A. Asiri, Muzaffar Iqbal, Alvin J. Beitz   +3 more
wiley   +1 more source

Development and Validation of a GC‐MS Method for the Detection and Quantification of Clotiapine in Blood and Urine Specimens and Application to a Postmortem Case

International Journal of Analytical Chemistry, Volume 2015, Issue 1, 2015., 2015
Introduction. Clotiapine is an atypical antipsychotic of the dibenzothiazepine class introduced in a few European countries since 1970, efficient in treatment‐resistant schizophrenic patients. There is little published data on the therapeutic and toxic concentrations of this drug. Aims.
Giulio Mannocchi, Flaminia Pantano, Roberta Tittarelli, Miriam Catanese, Federica Umani Ronchi, Francesco Paolo Busardò, Haopeng Wang   +6 more
wiley   +1 more source

ChemInform Abstract: STUDIES IN THE HETEROCYCLIC SERIES. PART 14. THE CHEMISTRY AND BIOLOGICAL ACTIVITY OF NEW AZA- AND THIA-PHENOTHIAZINES, AND RELATED DIBENZOTHIAZEPINES

Chemischer Informationsdienst, 1979
OKAFOR
core   +2 more sources

Validation of Quetiapine Fumarate in Pharmaceutical Dosage by Reverse‐Phase HPLC with Internal Standard Method

Journal of Chemistry, Volume 2013, Issue 1, 2013., 2013
A rapid, specific, and accurate isocratic HPLC method was developed and validated for the assay of quetiapine fumarate in pharmaceutical dosage forms. The assay involved an isocratic‐elution of quetiapine fumarate in Grace C18 column using mobile‐phase composition of 0.1% ortho phosphoric acid with triethyl amine as modifier buffer and acetonitrile in ...
Kiran B. Venkata, Sreenivas Rao Battula, Somshankar Dubey, Daryoush Afzali   +3 more
wiley   +1 more source

A Rapid and Selective LC‐MS/MS Method for Quantification of Quetiapine in Human Plasma and its Application to Pharmacokinetic Study on Indian Schizophrenia Patients

Journal of Chemistry, Volume 8, Issue 4, Page 1802-1814, 2011., 2011
A rapid, robust and selective high pressure liquid chromatography–positive electrospray ionization tandem mass spectrometry method has been developed and validated for the quantification of quetiapine (QUE) in human plasma with K2EDTA using oxcarbazepine (IS) as an internal standard.
S. Ravinder, A. T. Bapuji, K. Mukkanti, M. Nagesh, H. L. V. Ravikiran   +4 more
wiley   +1 more source

Synthesis of Aromatic Compounds [PDF]

, 1957
Not ...
Jarrett, Arthur D
core  

A Validated RP‐HPLC Method for the Estimation of Quetiapine in Bulk and Pharmaceutical Formulations

Journal of Chemistry, Volume 7, Issue S1, Page S261-S266, 2010., 2010
A new, simple, specific, sensitive, rapid, accurate and precise RP‐HPLC method was developed for the estimation of quetiapine in bulk and pharmaceutical formulations. Quetiapine was chromatographed on a reverse phase C18 Waters column (75x4.6 mm I.D., particle size 3.5 μm) in a mobile phase consisting of phosphate buffer (pH 3.0 adjusted with ...
D. Suneetha, A. Lakshmana Rao
wiley   +1 more source