Results 41 to 50 of about 82 (78)

Exciting progress in the transition metal‐catalyzed synthesis of oxepines, benzoxepines, dibenzoxepines, and other derivatives

Applied Organometallic Chemistry, 2021
AbstractFrom the past decade so far, the synthesis of seven‐membered oxacycles especially natural monocyclic oxepines and their annulated derivatives has received considerable attention. Due to the importance of these valuable scaffolds in natural products, pharmaceuticals, and prospective drugs, as well as their strong potential for use in the ...
Fatemeh Rafiee, Samira Hasani
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The synthesis of pacharin: a dibenzoxepine from the heartwood of Bauhinia racemosa Lamk.

Journal of the Chemical Society, Perkin Transactions 1, 1990
The synthesis of the novel dibenzoxepine derivative pacharin (13)(8-methoxy-7-methyldibenz[b,f]-oxepine-1,6-diol), a constituent of the heartwood of Bauhinia racemosa Lamk., is described The route depended on the formation of the diphenyl ether (8) which was converted by standard synthetic steps into the bisphosphonium salt (11).
Mark F. Comber, Melvyn V. Sargent
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Total synthesis of cularine alkaloids via dibenzoxepines as key intermediates

Tetrahedron, 1995
Abstract The total synthesis of several cularine alkaloids (cularine, oxocularine, dioxocularine and 4-hydroxycularine) via 10,11-dihydrodibenz(b,f)oxepin-10-ones as key intermediates is reported.
Alberto Garcia, Luis Castedo, Domingo Domínguez   +2 more
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Design, synthesis, cytotoxicities and DNA cleavage activities of dibenzoxepine and isoquinoline derivatives starting from dehydroabietylamine

Journal of Asian Natural Products Research, 2016
A series of novel hexahydrodibenzoxepine and quinazoline derivatives were designed and synthesized starting from dehydroabietylamine. The cytotoxicities of the compounds against L02 and HepG2 cell lines were investigated. Meanwhile, the plasmid DNA (Escherichia coli) cleavage of several heterocyclic derivatives was studied.
Chao-Xiang, Liu, Zhong-Xiang, Lin, Ai-Min, Zhou   +2 more
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ChemInform Abstract: A Synthetic Route to (.+‐.)‐Clavizepine Through a Dibenzoxepine Intermediate.

ChemInform, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. C. DE LA FUENTE, L. CASTEDO, D. DOMINGUEZ   +2 more
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Synthesis of Trifluoromethylated Dibenzoxepines via Palladium-Catalyzed Tandem C–O Bond Formation/C–H Arylation

The Journal of Organic Chemistry, 2023
A palladium-catalyzed cyclization reaction of phenols with trifluoromethyl-containing ortho-bromo-β-chlorostyrenes has been developed. In the presence of palladium(II) acetate, tricyclohexylphosphine, and cesium carbonate, a variety of 6-trifluoromethyldibenzo[b,d]oxepines were prepared in moderate to good yields through the tandem O-alkenylation of ...
Zhi-Yi Zhao, Xing-Guo Zhang, Hai-Yong Tu
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Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 1

Journal of Medicinal Chemistry, 1992
A series of 11-[[2-[(arylsulfonyl)amino]ethyl]thio]-6,11- dihydrodibenz[b,e]oxepin-2-carboxylic acids and related derivatives were synthesized. The compounds were tested for their antagonizing effects on guinea pig platelet TXA2/PGH2 receptors. Structure-activity relationships are discussed.
E, Ohshima, H, Takami, H, Sato, H, Obase, I, Miki, A, Ishii, A, Karasawa, K, Kubo   +7 more
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Photorearrangement of 9,10-epoxy-9,10-dihydrophenanthrene. Synthesis of 2,3:4,5-dibenzoxepin

Journal of the Chemical Society, Chemical Communications, 1973
9,10-Dihydro-9,10-epoxyphenanthrene undergoes photorearrangement to 1,2:3,4-dibenzoxepin, an unknown oxepin, which was synthesized independently.
N. E. Brightwell, G. W. Griffin
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Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 2

Journal of Medicinal Chemistry, 1992
A series of 11-[2-(1-benzimidazolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxep in-2- carboxylic acid derivatives and related compounds were synthesized and found to be potent TXA2/PGH2 receptor antagonists. Each compound synthesized was tested for its ability to displace [3H]U-46619 binding from guinea pig platelet TXA2/PGH2 receptors.
E, Ohshima, H, Takami, H, Sato, S, Mohri, H, Obase, I, Miki, A, Ishii, S, Shirakura, A, Karasawa, K, Kubo   +9 more
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ChemInform Abstract: Total Synthesis of Cularine Alkaloids via Dibenzoxepines as Key Intermediates.

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. GARCIA, L. CASTEDO, D. DOMINGUEZ
openaire   +1 more source