Results 121 to 130 of about 41,308 (256)

In vivo Dicer-2 interactome during viral infection reveals novel pro and antiviral factors in Drosophila melanogaster.

PLoS Pathogens
RNA interference has a major role in the control of viral infection in insects. It is initialized by the sensing of double stranded RNA (dsRNA) by the RNAse III enzyme Dicer-2.
Claire Rousseau, Thomas Morand, Gabrielle Haas, Emilie Lauret, Lauriane Kuhn, Johana Chicher, Philippe Hammann, Carine Meignin   +7 more
doaj   +1 more source

Serial H&E Pathology Reveals Progression‐Associated Nuclear Size Drift as a Longitudinal Digital Readout of Bladder Cancer Evolution

Advanced Science, EarlyView.
Routine serial H&E specimens from bladder cancer are converted into paired T0/T1 digital pathology readouts of tumor evolution. Progression is associated with longitudinal nuclear drift, with nuclear size‐related changes most evident in the independent confirmation cohort, alongside a broader spatial burden of increased nuclear area and biological ...
Xing Liu, Zhen‐Duo Shi, Gong‐Cheng Wang, Jian‐Ming Wang, Ying Liu, Yi Gong, Xuan Lin, Di Wu, Shi‐Chao Zhuo, Han Han, Yi‐Bing Shi, Fan‐Lai Meng, Yu Zhang, Zhi‐Gang Jia, Cong‐Hui Han   +14 more
wiley   +1 more source

USP7 reduces the level of nuclear DICER, impairing DNA damage response and promoting cancer progression

Molecular Oncology
Endoribonuclease DICER is an RNase III enzyme that mainly processes microRNAs in the cytoplasm but also participates in nuclear functions such as chromatin remodelling, epigenetic modification and DNA damage repair. The expression of nuclear DICER is low
Xiaojia Liu, Runhui Lu, Qianqian Yang, Jianfeng He, Caihu Huang, Yingting Cao, Zihan Zhou, Jiayi Huang, Lian Li, Ran Chen, Yanli Wang, Jian Huang, Ruiyu Xie, Xian Zhao, Jianxiu Yu   +14 more
doaj   +1 more source

Intestinal-epithelial-cell-specific Dicer gene ablation.

, 2013
a, Dicer protein expression levels in the isolated primary colonic epithelial cells of Dicerfl/fl control, VillinCre-DicerΔ/+, and VillinCre-DicerΔ/Δ mice. Representative western blotting images of three independent experiments are shown.
Young Jun Kang (247937), Motoyuki Otsuka (205227), Takeshi Yoshikawa (205236), Akemi Takata (205232), Kazuhiko Koike (135022), Motoko Ohno (452869), Chikako Shibata (205256), Haruhiko Yoshida (205264), Takahiro Kishikawa (205251)   +8 more
core   +1 more source

µSlicer for Programmable Multimaterial 3D Printing

Advanced Science, EarlyView.
ABSTRACT Nature rarely builds with uniform materials; instead, it achieves exceptional performance by arranging composition and structure across multiple length scales. Mimicking such architectures has become increasingly feasible with additive manufacturing, and especially with multimaterial 3D printing, where complex structures with spatially varying
Daniel H. Meile, Berin Šeta, Md. Tusher Mollah, Yohan Jacquet, Rob Wolfs, Jon Spangenberg   +5 more
wiley   +1 more source

Robust NbN‐on‐Si/SiGe Hybrid Microwave Quantum Circuits With Long‐Term Stability

Advanced Electronic Materials, EarlyView.
Superconducting NbN resonators integrated with Si/SiGe quantum wells based semiconducting chip are investigated as a CMOS–compatible platform for scalable quantum hardware. Temperature–dependent microwave spectroscopy reveals loss mechanisms from TLS, quasiparticles, and scattering.
Paniz Foshat, Samane Kalhor, Shima Poorgholam‐khanjari, Douglas Paul, Martin Weides, Kaveh Delfanazari   +5 more
wiley   +1 more source

Array‐Level Characterization of Cryogenic RRAM

Advanced Electronic Materials, EarlyView.
This paper reports the first array‐level comprehensive electrical characterization of a 1024‐device HfO2‐based RRAM array from 300, 77 to 4 K, covering forming, set/reset switching, endurance, retention, relaxation, and read disturb. The results manifest the high performance of RRAM array at cryogenic temperatures and huge application potential for ...
Yuyao Lu, Ruofei Hu, Zhixing Jiang, Feng Xu, Bin Gao, Jianshi Tang, He Qian, Huaqiang Wu   +7 more
wiley   +1 more source

Dicer partner proteins tune the length of mature miRNAs in flies and mammals

, 2013
Drosophila Dicer-1 produces microRNAs (miRNAs) from pre-miRNA, whereas Dicer-2 generates small interfering RNAs (siRNAs) from long dsRNA. Alternative splicing of the loquacious (loqs) mRNA generates three distinct Dicer partner proteins.
Fukunaga, Ryuya, Xu, Jia, Han, Bo W., Hung, Jui-Hung, Weng, Zhiping, Zamore, Phillip D.   +5 more
core   +1 more source

Controlling Self‐Doping in Conjugated Polyelectrolyte Copolymers to Vary the Threshold Voltage in OECTs

Advanced Electronic Materials, EarlyView.
Two series of self‐doped conjugated polyelectrolytes are synthesized from a non‐self‐dopable building block 3MEEET and a self‐dopable building‐block 3HOT−[TMA+] or 3HOT−[SO3H] enabling precise control over the degree of self‐doping, which in turn directly governs the threshold voltage (VT) in OECTs over a wide range of 700 mV.
Julian Hungenberg, Andreas W. Erhardt, Adrian Hochgesang, John Mohanraj, Lys Sprenger, Sahar Salehi, Christopher R. McNeill, Mukundan Thelakkat   +7 more
wiley   +1 more source

Loqs Associates with Dicer-1

, 2013
(A) Loqs and Dicer-1 form a complex in vivo. Left panel: Protein extract was prepared from S2 cells that expressed both full-length myc-tagged Loqs (myc-Loqs) and Flag-tagged Dicer-1 (Flag-Dcr-1).
Haruhiko Siomi (9423), Kuniaki Saito (9421), Mikiko C Siomi (9424), Akira Ishizuka (9422)   +3 more
core   +1 more source