Results 41 to 50 of about 75,724 (336)
Journal of International Medical Research, 2021 Objective This study explored the functional interactions between the long non-coding RNA DICER-AS1 and the cellular stress response 1 ( CSR1 ) gene in gastric cancer.
Junyan An, Xiaoling Guo, Bingli Yan
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MicroRNAs Regulate Ca2+ Homeostasis in Murine Embryonic Stem Cells
Cells, 2023 MicroRNAs (miRNAs) are important regulators of embryonic stem cell (ESC) biology, and their study has identified key regulatory mechanisms. To find novel pathways regulated by miRNAs in ESCs, we undertook a bioinformatics analysis of gene pathways ...
Kimberley M. Reid +7 more
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Characterization of Dicer-deficient murine embryonic stem cells [PDF]
, 2005 Dicer is an RNase III-family nuclease that initiates RNA interference (RNAi) and related phenomena by generation of the small RNAs that determine the specificity of these gene silencing pathways.
Cheloufi, S. +4 more
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Global microRNA expression is essential for murine mast cell development in vivo [PDF]
, 2014 MicroRNAs (miRNAs) are small, noncoding RNAs that have been shown to play a critical role in normal physiology and disease, such as hematopoietic development and cancer. However, their role in mast-cell function and development is poorly understood.
Brandal, Stephanie +4 more
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Role of Dicer in female fertility [PDF]
Trends in Endocrinology & Metabolism, 2009 Dicer is an RNAse III endonuclease that is essential for the biogenesis of microRNAs and small interfering RNAs. These small RNAs post-transcriptionally regulate mRNA gene expression through several mechanisms to affect key cellular events including proliferation, differentiation and apoptosis.
Martha Z. Carletti +2 more
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Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein.
PLoS Genetics, 2016 Dicer is a large multi-domain protein responsible for the ultimate step of microRNA and short-interfering RNA biogenesis. In human and mouse cell lines, Dicer has been shown to be important in the nuclear clearance of dsRNA as well as the establishment ...
Christian Much +7 more
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Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects
Molecular Metabolism, 2019 Objective: Dietary restriction (DR) improves health and prolongs lifespan in part by upregulating type III endoribonuclease DICER in adipose tissue. In this study, we aimed to specifically test which missing dietary component was responsible for DICER ...
Beatriz A. Guerra +13 more
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Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]
, 2013 RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif +2 more
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Nature Reviews Cancer, 2010 A new family of microRNAs induces epithelial–mesenchymal transition and metastases formation by inhibiting DICER.
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Journal of Experimental & Clinical Cancer Research, 2019 Background CyclinD1 is crucial for cell cycling and can regulate the expression of Dicer, a crucial regulator of microRNA maturation. However, little is known on how CyclinD1 regulates Dicer and miRNA expression, and the progression of intrahepatic ...
Yongqiang Qi +7 more
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