Results 51 to 60 of about 34,642 (262)

Cause or Effect: Misregulation of MicroRNA Pathways in Neurodegeneration

Frontiers in Neuroscience, 2012
During normal aging or neurodegenerative diseases, neuronal survival and function depend on protein homeostasis, which is regulated by multiple mechanisms, including the microRNA (miRNA) pathway.
Fen-Biao eGao, Eduardo eGascon
doaj   +1 more source

Rationally Designed Bilayer Passivation Strategy for High‐Performance Vacuum‐Processed Perovskite Solar Cells

Advanced Functional Materials, EarlyView.
A bilayer “Anchor‐and‐Seal” passivation strategy using EDAI2 and 4MeO‐PEAI effectively mitigates surface defects in vacuum‐processed perovskite films through synergistic hydrogen bonding and Lewis base coordination. This approach optimizes interfacial energy alignment and suppresses non‐radiative recombination, enabling vacuum‐deposited p‐i‐n ...
Mohammadhossein Kohan, Sang‐Heon Lee, Jaswinder Singh, Sung‐Nam Kwon, Seok‐In Na   +4 more
wiley   +1 more source

Dicer is associated with ribosomal DNA chromatin in mammalian cells. [PDF]

PLoS ONE, 2010
BACKGROUND: RNA silencing is a common term for pathways utilizing small RNAs as sequence-specific guides to repress gene expression. Components of the RNA silencing machinery are involved in different aspects of chromatin function in numerous organisms ...
Lasse Sinkkonen, Tabea Hugenschmidt, Witold Filipowicz, Petr Svoboda   +3 more
doaj   +1 more source

RNAi-Related Dicer and Argonaute Proteins Play Critical Roles for Meiocyte Formation, Chromosome-Axes Lengths and Crossover Patterning in the Fungus Sordaria macrospora

Frontiers in Cell and Developmental Biology, 2021
RNA interference (RNAi) is a cellular process involving small RNAs that target and regulate complementary RNA transcripts. This phenomenon has well-characterized roles in regulating gene and transposon expression.
Chloe Girard, Karine Budin, Stéphanie Boisnard, Liangran Zhang, Robert Debuchy, Denise Zickler, Eric Espagne   +6 more
doaj   +1 more source

Template‐Confined Synthesis of Shape‐Engineered Single‐Crystal Gold Microplates in Lithographically‐Defined Polymeric Patterns

Advanced Functional Materials, EarlyView.
Single‐crystal gold microplates are high‐performance nanomaterials with an impressive wafer‐based application space. Progress has, however, been tempered by an inability to exert synthetic control over microplate size, shape, and positioning. In this work, control over these parameters is demonstrated using a seed‐mediated synthesis that both confines ...
Debasish Panda, Md Rashed Nizam, Walker J. Tuff, Collin C. Wyant, Maksym Zhukovskyi, Matthew R. Rosenberger, Botond Sánta, Edward C. Kinzel, Robert A. Hughes, Svetlana Neretina   +9 more
wiley   +1 more source

Dicer Functions in Aquatic Species [PDF]

Journal of Amino Acids, 2011
Dicer is an RNase III enzyme with two catalytic subunits, which catalyzes the cleavage of double-stranded RNA to small interfering RNAs and micro-RNAs, which are mainly involved in invasive nucleic acid defense and endogenous genes regulation. Dicer is abundantly expressed in embryos, indicating the importance of the protein in early embryonic ...
Yasuko Kitagishi, Naoko Okumura, Hitomi Yoshida, Chika Tateishi, Yuri Nishimura, Satoru Matsuda   +5 more
openaire   +2 more sources

Generation of Virus- and dsRNA-Derived siRNAs with Species-Dependent Length in Insects

Viruses, 2019
Double-stranded RNA (dsRNA) molecules of viral origin trigger a post-transcriptional gene-silencing mechanism called RNA interference (RNAi). Specifically, virally derived dsRNA is recognized and cleaved by the enzyme Dicer2 into short interfering RNAs ...
Dulce Santos, Lina Mingels, Elise Vogel, Luoluo Wang, Olivier Christiaens, Kaat Cappelle, Niels Wynant, Yannick Gansemans, Filip Van Nieuwerburgh, Guy Smagghe, Luc Swevers, Jozef Vanden Broeck   +11 more
doaj   +1 more source

Designing Stable Periodic Magnetization Textures by Tailoring Anisotropies and Applying Geometrical Transformation

Advanced Functional Materials, EarlyView.
This work explores the possibility to design stable periodic magnetization textures by transforming a 2D film into a rolled‐up 3D architecture and back. In case of an isotropic exchange‐biased layer architecture, the magnetization encoded in the 3D state evolves into a spin‐spiral pattern with controlled periodicity after unrolling.
Aman Singh, Ivan Soldatov, Rudolf Schäfer, Volker Neu   +3 more
wiley   +1 more source

A Deathly DNase Activity for Dicer [PDF]

Developmental Cell, 2010
Recently reporting in Science, Nakagawa et al. describe an unexpected role for Dicer in chromosome fragmentation during apoptosis in C. elegans. They find that cleavage of DCR-1 by the caspase CED-3 redirects its regulatory activity, by destroying its dsRNase activity while activating an intrinsic DNase activity.
Okamura, Katsutomo, Lai, Eric C.
openaire   +2 more sources

Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function. [PDF]

PLoS ONE, 2011
Phenotypic modulation of smooth muscle cells (SMCs) plays a key role in vascular disease, including atherosclerosis. Several transcription factors have been suggested to regulate phenotypic modulation of SMCs but the decisive mechanisms remain unknown ...
Sebastian Albinsson, Athanasia Skoura, Jun Yu, Annarita DiLorenzo, Carlos Fernández-Hernando, Stefan Offermanns, Joseph M Miano, William C Sessa   +7 more
doaj   +1 more source