Results 71 to 80 of about 41,308 (256)
Dicer loss compromises viability during unconstrained Kras driven ADM.
, 2014 (A–D) TUNEL (blue) and YFP (green) staining in 3 weeks old DicerHet; YFP (A), DicerHomo; YFP (B), Kras; DicerHet; YFP (C), and Kras; DicerHomo; YFP mice (D). Scale bar 100 µM. E. Quantification of TUNEL+YFP+ cells in (A-D). Mean ± SD.
Guido von Figura (229502) +10 more
core +1 more source
Epitaxially Integrated Electro‐Optic KNbO3 Thin Films on Silicon
Advanced Materials, EarlyView.We demonstrate the first epitaxial integration of electro‐optic KNbO3 thin films on silicon using suboxide molecular‐beam epitaxy. Combining adsorption‐controlled molecular‐beam epitaxy, advanced characterization, and phase‐field modeling, we demonstrate phase‐pure crystalline films mirroring bulk crystals with robust Pockels response, enabling future ...
Sankalpa Hazra +17 more
wiley +1 more source
, 2003 Posttranscriptional silencing (PTGS) in plants, nematodes, Drosophila, and perhaps all eukaryotes operates by sequence-specific degradation or translational inhibition of the target mRNA. These processes are mediated by duplexed RNA.
Finnegan, E. Jean +2 more
core +1 more source
Chiral Phonon–Driven Ultrafast Spin Currents in a Non‐Magnetic Ferroelectric
Advanced Materials, EarlyView.Broadband terahertz emission spectroscopy shows signatures of ultrafast spin‐current generation in non‐magnetic ferroelectric β$\beta$’‐In2Se3${\rm In}_2{\rm Se}_3$. Reversal of the emitted field upon sample inversion and substitution of Pt with W indicates spin‐Hall‐mediated charge conversion, while polarization‐resolved measurements reveal ...
Thomas B. Gill +16 more
wiley +1 more source
The EMBO JournalIn mammalian somatic cells, the relative contribution of RNAi and the type I interferon response during viral infection is unclear. The apparent inefficiency of antiviral RNAi might be due to self-limiting properties and mitigating co-factors of the key ...
Morgane Baldaccini +5 more
doaj +1 more source
Microscale 3D‐Printed Digital Strain Switches for Embedded Mechanical Computation
Advanced Materials Technologies, EarlyView.Microscale 3D‐printed strain switches on flexible films convert deformation into native digital signals at geometry defined thresholds. A closed form model predicts switching from 3000 to 15 000 microstrain and is validated across 110 devices. Reliable ohmic closure and strain activated AND, OR, and XOR logic point toward low‐power mechanical ...
Regan Kubicek +3 more
wiley +1 more source
Expression levels of microRNA machinery components Drosha, Dicer and DGCR8 in human (AGS, HepG2, and KEYSE-30) cancer cell lines [PDF]
: MicroRNAs (miRNAs) have recently been shown to play fundamental roles in diverse cellular processes and linked to variety of cancers. Dicer and Drosha are tw major enzymes in the miRNA maturation process.
حسینی اصل, سید سعید +7 more
core
Disruption of DICER impairs miRNA biogenesis.
, 2013 A) QRT-PCR for pri-miR-17 in HCT116 WT and Exn5/Exn5 cells. B) QRT-PCR for miRNAs of the miR-17-92 cluster and others in HCT116 WT and Exn5/Exn5 cells. C) QRT-PCR for Dicer mRNA in HCT116 EV and DICER shRNA cells. D) QRT-PCR for Pri-miRNA-17 in HCT116 EV
Susan E. Logue (447410) +6 more
core +1 more source
Journal of Hepatocellular Carcinoma, 2021 Cuiju Wang,1 Yalei Lv,2 Ziyue Sha,3 Jingjing Zhang,3 Jianhua Wu,4 Yixin Qi,5 Zhanjun Guo3 1Department of Gynaecology Ultrasound, The Fourth Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Medical Oncology ...
Wang C +6 more
doaj
Dicer loss promotes Kras driven loss of acinar identity and ductal reprogramming.
, 2014 (A–D) Clusterin (blue) and YFP (green) staining in 3 week old DicerHet; YFP (A), DicerHomo; YFP (B), Kras; DicerHet; YFP (C), and Kras; DicerHomo; YFP mice (D).
Guido von Figura (229502) +10 more
core +1 more source