Results 91 to 100 of about 41,308 (256)
, 2014 A) Indistinguishable appearance of Dicer-conditional littermates with (DicerΔ/Δ) or without (Dicerc/c) the K5-Cre transgene at four weeks of age. B) Normal morphology of skin and hair follicles in four-week old control mice (Dicerc/c mice, left two ...
Zdenka Matijasevic (590631) +5 more
core +1 more source
Advanced Science, EarlyView.TAB–2TFSI enables efficient ion‐pair doping across a wide range of conjugated polymers, where the strongly oxidizing TAB core drives charge transfer, and the TFSI counterions promote favorable ionic compensation. This dicationic dopant promotes uniform dopant distribution, improves structural order, and increases carrier delocalization, establishing a ...
Juhyung Park +14 more
wiley +1 more source
Kras driven PanIN and PDA progression in Dicer conditional mice.
, 2014 (A–B) Representative Alcian Blue staining at 9 weeks in Kras; DicerHet (A) and Kras; DicerHomo mice (B). f: fat. Scale bar 100 µM. C, Quantification of alcian blue positive lesions of 9 weeks old Kras; DicerHet and Kras; DicerHomo mice.
Guido von Figura (229502) +10 more
core +1 more source
Advanced Science, EarlyView.MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo +6 more
wiley +1 more source
Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy
Advanced Science, EarlyView.This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo +7 more
wiley +1 more source
Effect of endothelial microRNAs on blood pressure homeostasis
Journal of Physical Fitness and Sports Medicine, 2018 Endothelial function is an important factor for maintenance of blood pressure (BP) homeostasis. Recently, microRNA (miRNA) has emerged as a potential regulator of endothelial function.
Satoshi Oikawa +2 more
doaj +1 more source
Deletion of Dicer induces loss of polarity in acinar cells following Dicer deletion.
, 2014 (A) Epithelial cell polarity marker CD49f (white) is expressed basally, while phalloidin labeling (red) is observed apically in control Mist-CreERT2; LSL-YFP; Dicerwt/wt pancreas following tamoxifen treatment. (B) In the Mist-CreERT2; LSL-YFP; Dicerfl/fl
Jennifer M. Bailey (470774) +6 more
core +1 more source
Dicer regulates Nosema ceranae proliferation in honeybees
, 2019 osema ceranae is a microsporidian parasite which infects the honey bee mid‐gut epithelium. The protein coding gene Dicer, is lost in most microsporidian genomes, but is present in N. ceranae.
Neumann, Peter +6 more
core +2 more sources
Calvarial Characterization of Dicer-Deficient under Sost Promotor Mouse Model
, 2023 This study aims to evaluate the roles of mature miRNAs in osteocytes of calvarial bones. The skulls of transgenic Dicer deficiency driven under Sost (Dicer/Sost KO) mice were compared to the age and sex-matched control mice (Dicer floxed and Sostcre). We
Youngjae Sung (15107353)
core +1 more source
Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics
Advanced Science, EarlyView.This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka +3 more
wiley +1 more source