Results 71 to 80 of about 77,494 (336)
Advanced Functional Materials, EarlyView.Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee +9 more
wiley +1 more source
Cause or Effect: Misregulation of MicroRNA Pathways in Neurodegeneration
Frontiers in Neuroscience, 2012 During normal aging or neurodegenerative diseases, neuronal survival and function depend on protein homeostasis, which is regulated by multiple mechanisms, including the microRNA (miRNA) pathway.
Fen-Biao eGao, Eduardo eGascon
doaj +1 more source
Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation. [PDF]
PLoS ONE, 2015 Dicer, a ribonuclease III enzyme, is required for the maturation of microRNAs. To assess its role in cerebellar and medulloblastoma development, we genetically deleted Dicer in Nestin-positive neural progenitors and in mice lacking one copy for the Sonic
Frederique Zindy +7 more
doaj +1 more source
Emerging connections between small RNAs and phytohormones [PDF]
, 2020 Small RNAs (sRNAs), mainly including miRNAs and siRNAs, are ubiquitous in eukaryotes. sRNAs mostly negatively regulate gene expression via (post-)transcriptional gene silencing through DNA methylation, mRNA cleavage, or translation inhibition.
Dubois, Marieke +3 more
core +2 more sources
Pseudospin-one particles in the time-periodic dice lattice: a new approach to transport control [PDF]
, 2022 Parisa Majari
openalex +1 more source
Advanced Functional Materials, EarlyView.Molecular engineering of a nonconjugated radical polymer enables a significant enhancement of the glass transition temperature. The amorphous nature and tunability of the polymer, arising from its nonconjugated backbone, facilitates the fabrication of organic memristive devices with an exceptionally high yield (>95%), as well as substantial ...
Daeun Kim +14 more
wiley +1 more source
Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome [PDF]
, 2018 Background: Genetic classification of breast cancer based on the coding mRNA suggests the evolution of distinct subtypes. Whether the non-coding genome is altered concordantly with the coding genome and the mechanism by which the cell cycle directly ...
Addya, Sankar +16 more
core +2 more sources
Loss of Dicer in Newborn Melanocytes Leads to Premature Hair Graying and Changes in Integrin Expression [PDF]
, 2023 Juliette Bertrand +8 more
openalex +1 more source
3D Digital Light Processing of Redox‐Active Polymers for Electrochemical Applications
Advanced Functional Materials, EarlyView.3D printing of electrochemically switchable conducting polymers is achieved by Digital Light Processing of redox‐active carbazole‐based polymer materials. Complex 2D and 3D architectures including dot arrays and pyramids clearly show the potential for novel 3D switchable electrochemical devices for sensors, electrochromic displays as well as 3D printed
Christian Delavier +4 more
wiley +1 more source
Generation of Virus- and dsRNA-Derived siRNAs with Species-Dependent Length in Insects
Viruses, 2019 Double-stranded RNA (dsRNA) molecules of viral origin trigger a post-transcriptional gene-silencing mechanism called RNA interference (RNAi). Specifically, virally derived dsRNA is recognized and cleaved by the enzyme Dicer2 into short interfering RNAs ...
Dulce Santos +11 more
doaj +1 more source