Results 71 to 80 of about 102,919 (290)

Effect of iguratimod on diclofenac metabolism by CYP2C9 in rats and human recombinant CYP2C9 yeast cells

Brazilian Journal of Pharmaceutical Sciences
Iguratimod (IGU, also known as T-614), a novel disease modifying antirheumatic drug intended to cure patients with rheumatoid arthritis (RA). The purpose of this study is to evaluate the effect of IGU on the pharmacokinetics of CYP2C9 probe drug ...
Muhammad Usman, Zhu Zhen-Han, Chang Ze-Na, Han Jun-Ping, Qian Wen, Yang Chang-Qing, Nishikawa Miyu, Sakaki Toshiyuki   +7 more
doaj   +1 more source

Effect of Amoxicillin And Cefalexin on The Pharmacokinetics of Diclofenac Sodium in Healthy Volunteers [PDF]

The Medical Journal of Basrah University, 2015
Background: Studies investigating the effect of antibiotics on the pharmacokinetics of non-steroidal anti-inflammatory drugs are few. Such interaction could be clinically significant in conditions like diabetic nephropathy.
Shaima M. Ali, Nazar Haddad, Abdullah M. Jawad   +2 more
doaj   +1 more source

Targeted monitoring for human pharmaceuticals in vulnerable source and final waters [PDF]

, 2012
A range of pharmaceuticals has been detected in soils, surface waters and groundwaters across the world. While the reported concentrations are generally low (i.e. sub μg l-1 in surface waters), the substances have been observed throughout the year across
Bersuder, Phillipe, Boxall, Alistair B.A., Bruemer, Janine, Fussell, Richard, Greenwood, Richard, Monteiro, Sara C., Williams, Richard J.   +6 more
core  

Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy [PDF]

, 2017
BACKGROUND. Actinic keratosis is a precursor to cutaneous squamous cell carcinoma. Long treatment durations and severe side effects have limited the efficacy of current actinic keratosis treatments.
Ahu Turkoz, Andras Schaffer, Arturo P. Saavedra, Cipolat, Fenske, Hengameh Mirzaalian, Jean-Pierre Eliane, Lynn A. Cornelius, Mary Tabacchi, Michael Wallendorf, Raphael Kopan, Salasche, Sara Moradi Tuchayi, Seckin, Shadmehr Demehri, Sindhu Manivasagam, Stockfleth, Trevor J. Cunningham, Warino   +18 more
core   +2 more sources

Effect of surgical antimicrobial prophylaxis duration for colic surgery on complications and resistome

Equine Veterinary Journal, EarlyView.
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood, Alicia Long, Jairo Perez, Scott Daniel, Kyle Bittinger, Maia Aitken, Laurel Redding   +6 more
wiley   +1 more source

Importance of the formulation in the skin delivery of topical diclofenac: not all topical diclofenac formulations are the same

Journal of Pain Research, 2019
Julie Pradal, Coralie M Vallet, Guillaume Frappin, Frédérique Bariguian, Maria Stella LombardiDepartment of New Product Development, R&D, GSK Consumer Healthcare S.A, Nyon 1, 1260, SwitzerlandPurpose: The current study aimed to compare ...
Pradal J, Vallet CM, Frappin G, Bariguian F, Lombardi MS   +4 more
doaj  

The efficacy of transdermal and oral diclofenac for post-endodontic pain control: A randomised controlled trial

Indian Journal of Dental Research, 2020
Objective: The aim of the present study was to compare the effect of transdermal diclofenac patch against oral diclofenac for post-endodontic pain control. Materials and Methods: Thirty-two patients with symptomatic irreversible pulpitis in single-rooted
Shivani Mangal, Sylvia Mathew, B V Sreenivasa Murthy, Swaroop Hegde, K Dinesh, Poornima Ramesh   +5 more
doaj   +1 more source

Disease activity and cognition in rheumatoid arthritis : an open label pilot study [PDF]

, 2012
Acknowledgements This work was supported in part by NIHR Newcastle Biomedical Research Centre. Funding for this study was provided by Abbott Laboratories.
Birchall, Daniel, Blamire, Andrew M, He, Jiabao, Isaacs, John D, Newton, Julia L, Pearce, Ruth, Raftery, Graham   +6 more
core   +1 more source

Diclofenac Induced Rapidly Progressive Renal Failure in Elderly Patient – A Case Report [PDF]

, 2022
C Chandana, Srirangam Anusha, H B Kavya
openalex   +1 more source

Effects of diclofenac on the pharmacokinetics of celastrol in rats and its transport

Pharmaceutical Biology, 2018
Context: Diclofenac and celastrol are always used together for the treatment of rheumatoid arthritis; the herb–drug interaction potential between diclofenac and celastrol is still unknown.
Zengfu Wang, Dali Chen, Zhongwei Wang
doaj   +1 more source