Results 111 to 120 of about 28,160 (153)

The green tea catechin epigallocatechin gallate (EGCG) blocks cell motility, chemotaxis and development in Dictyostelium discoideum.

open access: yesPLoS ONE, 2013
Catechins, flavanols found at high levels in green tea, have received significant attention due to their potential health benefits related to cancer, autoimmunity and metabolic disease, but little is known about the mechanisms by which these compounds ...
Kyle J McQuade   +4 more
doaj   +1 more source

Fat-containing cells are eliminated during Dictyostelium development

open access: yesBiology Open, 2017
Triacylglycerol is a universal storage molecule for metabolic energy in living organisms. However, Dictyostelium amoebae, that have accumulated storage fat from added fatty acids do not progress through the starvation period preceding the development of ...
Jessica M. Kornke, Markus Maniak
doaj   +1 more source

Chromatin Structure in the Cellular Slime Mold Dictyostelium discoideum [PDF]

open access: yes, 1978
The structure of Dictyostelium discoideum chromatin has been studied by the following techniques: electron microscopy, staphylococcal nuclease digestion, acrylamide gel electrophoresis, sucrose gradient centrifugation, and melting.
Bakke, Antony C.   +2 more
core  

Dictyostelium as a model for human disease [PDF]

open access: yesSeminars in Cell & Developmental Biology, 2011
Peer ...
openaire   +3 more sources

Regulation of Dictyostelium morphogenesis by RapGAP3

open access: yesDevelopmental Biology, 2009
Rap1 is a key regulator of cell adhesion and cell motility in Dictyostelium. Here, we identify a Rap1-specific GAP protein (RapGAP3) and provide evidence that Rap1 signaling regulates cell-cell adhesion and cell migration within the multicellular organism.
Gerald Weeks   +3 more
openaire   +3 more sources

Modelling of Neuronal Ceroid Lipofuscinosis Type 2 in Dictyostelium discoideum Suggests That Cytopathological Outcomes Result from Altered TOR Signalling

open access: yesCells, 2019
The neuronal ceroid lipofuscinoses comprise a group of neurodegenerative disorders with similar clinical manifestations whose precise mechanisms of disease are presently unknown.
Paige K. Smith   +3 more
doaj   +1 more source

Convective Instability and Boundary Driven Oscillations in a Reaction-Diffusion-Advection Model

open access: yes, 2017
In a reaction-diffusion-advection system, with a convectively unstable regime, a perturbation creates a wave train that is advected downstream and eventually leaves the system.
Bodenschatz, Eberhard   +3 more
core   +1 more source

Evidence for nucleolar subcompartments in Dictyostelium

open access: yesBiochemical and Biophysical Research Communications, 2015
The nucleolus is a multifunctional nuclear compartment usually consisting of two to three subcompartments which represent stages of ribosomal biogenesis. It is linked to several human diseases including viral infections, cancer, and neurodegeneration.
Danton H. O'Day, Andrew Catalano
openaire   +3 more sources

Dictyostelium discoideum protocols

open access: yesEuropean Journal of Histochemistry, 2013
As well highlighted and stressed by the two editors (Ludwig Eichinger, Center for Biochemistry, Medical Faculty, University of Cologne, Köln, Germany and Francisco Rivero, Center for Cardiovascular and Metabolic research, the Hull York Medical School, University of Hull, UK), Dictyostelium discoideum is an acclaimed member of the so-called model ...
openaire   +4 more sources

Diverse Roles of the Multiple Phosphodiesterases in the Regulation of Cyclic Nucleotide Signaling in Dictyostelium

open access: yesCells
Dictyostelium is a unique model used to study the complex and interactive cyclic nucleotide signaling pathways that regulate multicellular development.
Pundrik Jaiswal, Alan R. Kimmel
doaj   +1 more source

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