Results 31 to 40 of about 38,088 (249)

Recent Insights into NCL Protein Function Using the Model Organism Dictyostelium discoideum

open access: yesCells, 2019
The neuronal ceroid lipofuscinoses (NCLs) are a group of devastating neurological disorders that have a global distribution and affect people of all ages.
Meagan D. McLaren   +2 more
semanticscholar   +1 more source

Models of aggregation in dictyostelium discoideum: On the track of spiral waves

open access: yesNetworks and Heterogeneous Media, 2006
This work is concerned with some aspects of the social life of theamoebae Dictyostelium discoideum (Dd). In particular, we shall focus on the early stages of the starvation-induced aggregation of Dd cells.
Miguel A. Herrero, Leandro Sastre
doaj   +1 more source

Development of a Positive Selection High Throughput Genetic Screen in Dictyostelium discoideum

open access: yesFrontiers in Cell and Developmental Biology, 2021
The cellular slime mold Dictyostelium discoideum is a powerful model organism that can be utilized to investigate human health and disease. One particular strength of Dictyostelium is that it can be utilized for high throughput genetic screens.
Felicia N. Williams   +4 more
doaj   +1 more source

Investigation of a potential role for aldose reductase AlrA in tetrahydropteridine synthesis in Dictyostelium discoideum Ax2

open access: yesPteridines, 2017
Dictyostelium discoideum Ax2 is well-known for the synthesis of d-threo-tetrahydrobiopterin (DH4) with a smaller amount of l-erythro-tetrahydrobiopterin (BH4).
Kim Hye-Lim   +2 more
doaj   +1 more source

Exploring Virulence Determinants of Filamentous Fungal Pathogens through Interactions with Soil Amoebae

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Infections with filamentous fungi are common to all animals, but attention is rising especially due to the increasing incidence and high mortality rates observed in immunocompromised human individuals. Here, Aspergillus fumigatus and other members of its
Silvia Novohradská   +4 more
doaj   +1 more source

Dictyostelium discoideum as a Model for Investigating Neurodegenerative Diseases

open access: yesFrontiers in Cellular Neuroscience, 2021
The social amoeba Dictyostelium discoideum is a model organism that is used to investigate many cellular processes including chemotaxis, cell motility, cell differentiation, and human disease pathogenesis.
Holly N. Haver   +3 more
doaj   +1 more source

Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions

open access: yesPLoS Pathogens, 2017
During a tuberculosis infection and inside lipid-laden foamy macrophages, fatty acids (FAs) and sterols are the major energy and carbon source for Mycobacterium tuberculosis.
Caroline Barisch, Thierry Soldati
semanticscholar   +1 more source

TheDictyosteliumGenome [PDF]

open access: yesCurrent Issues in Molecular Biology, 2006
The 34 Mb genome of Dictyostelium discoideum is carried on 6 chromosomes and has been fully sequenced by an international consortium. The sequence was assembled on the classical and physical maps that had been built up over the years and refined by HAPPY mapping.
openaire   +2 more sources

The physiological regulation of macropinocytosis during Dictyostelium growth and development

open access: yesJournal of Cell Science, 2017
Macropinocytosis is a conserved endocytic process used by Dictyostelium amoebae for feeding on liquid medium. To further Dictyostelium as a model for macropinocytosis, we developed a high-throughput flow cytometry assay to measure macropinocytosis, and ...
Thomas D. Williams, R. Kay
semanticscholar   +1 more source

Perspective on Interdisciplinary Approaches on Chemotaxis. [PDF]

open access: yesAngew Chem Int Ed Engl
Chemotaxis is the movement of individual organisms towards or away from a chemical stimulus. This phenomenon is investigated in various disciplines, ranging from biology to physics and even engineering. This perspective aims to summarise recent developments in the field and encourage the unification of terminology to promote interdisciplinary knowledge
Simmchen J   +18 more
europepmc   +2 more sources

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