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Dictyostelium discoideum as a non‐mammalian biomedical model
Microbial Biotechnology, 2021 Summary Dictyostelium discoideum is one of eight non‐mammalian model organisms recognized by the National Institute of Health for the study of human pathology. The use of this slime mould is possible owing to similarities in cell structure, behaviour and
Javier Martín‐González +2 more
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Frontiers in Microbiology, 2016 The social amoeba Dictyostelium discoideum is a well-established model organism to study the interaction between bacteria and phagocytes. In contrast, research using D. discoideum as a host model for fungi is rare.
Barbara Koller +8 more
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Endosymbiotic adaptations in three new bacterial species associated with Dictyostelium discoideum: Paraburkholderia agricolaris sp. nov., Paraburkholderia hayleyella sp. nov., and Paraburkholderia bonniea sp. nov [PDF]
PeerJ, 2020 Here we give names to three new species of Paraburkholderia that can remain in symbiosis indefinitely in the spores of a soil dwelling eukaryote, Dictyostelium discoideum. The new species P. agricolaris sp. nov., P. hayleyella sp. nov., and P. bonniea sp.
Debra A. Brock +10 more
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Multi-color fluorescence live-cell imaging in Dictyostelium discoideum [PDF]
Cell Structure and FunctionThe cellular slime mold Dictyostelium discoideum, a member of the Amoebozoa, has been extensively studied in cell and developmental biology. D. discoideum is unique in that they are genetically tractable, with a wealth of data accumulated over half a ...
Hidenori Hashimura +8 more
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Flow-driven instabilities during pattern formation of Dictyostelium discoideum
New Journal of Physics, 2015 The slime mold Dictyostelium discoideum is a well known model system for the study of biological pattern formation. In the natural environment, aggregating populations of starving Dictyostelium discoideum cells may experience fluid flows that can ...
A Gholami +3 more
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BioTechniques, 2013 The loading controls used for quantitative immunoblotting of mammalian proteins are not appropriate for use with Dictyostelium discoideum. Actin levels, for example, change greatly during Dictyostelium development.
Andrew J. Davidson +2 more
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Transcriptomic and metabolomic insights into light-mediated unicellular-to-multicellular transition in Dictyostelium discoideum [PDF]
Open BiologyDictyostelium discoideum is a social amoeba that transitions from unicellular to multicellular forms in response to environmental signals, making it an intriguing model for studying cell aggregation and differentiation.
Yuehui Tian +6 more
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Frontiers in Cellular and Infection Microbiology, 2018 Inorganic polyphosphate (polyP) deficiency in enteric bacterial pathogens reduces their ability to invade and establish systemic infections in different hosts.
Macarena A. Varas +6 more
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Ion Signaling in Cell Motility and Development in Dictyostelium discoideum [PDF]
BiomoleculesCell-to-cell communication is fundamental to the organization and functionality of multicellular organisms. Intercellular signals orchestrate a variety of cellular responses, including gene expression and protein function changes, and contribute to the ...
Yusuke V. Morimoto
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Frontiers in Neuroscience, 2022 Microsatellites are repetitive sequences commonly found in the genomes of higher organisms. These repetitive sequences are prone to expansion or contraction, and when microsatellite expansion occurs in the regulatory or coding regions of genes this can ...
Felicia N. Williams +3 more
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