Results 11 to 20 of about 41,925 (254)

Dictyostelium discoideum protocols

open access: yesEuropean Journal of Histochemistry, 2013
As well highlighted and stressed by the two editors (Ludwig Eichinger, Center for Biochemistry, Medical Faculty, University of Cologne, Köln, Germany and Francisco Rivero, Center for Cardiovascular and Metabolic research, the Hull York Medical School ...
Carlo Alberto Redi
doaj   +4 more sources

A recombinant antibody toolbox for Dictyostelium discoideum

open access: yesBMC Research Notes, 2020
Objective The amoeba Dictyostelium discoideum has been a valuable model organism to study numerous facets of eukaryotic cell biology, such as cell motility, cell adhesion, macropinocytosis and phagocytosis, host–pathogen interactions and multicellular ...
Wanessa C. Lima   +2 more
doaj   +1 more source

Stochastic noise and synchronisation during Dictyostelium aggregation make cAMP oscillations robust [PDF]

open access: yes, 2007
The molecular network, which underlies the oscillations in the concentration of adenosine 3′, 5′-cyclic monophosphate (cAMP) during the aggregation phase of starvation-induced development in Dictyostelium discoideum, achieves remarkable levels of robust ...
Bates, Declan   +3 more
core   +14 more sources

A RabGAP regulates life-cycle duration via trimeric G-protein cascades in Dictyostelium discoideum. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: The life-cycle of cellular slime molds comprises chronobiologically regulated processes. During the growth phase, the amoeboid cells proliferate at a definite rate.
Hidekazu Kuwayama   +3 more
doaj   +1 more source

Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of Dictyostelium discoideum

open access: yesG3: Genes, Genomes, Genetics, 2020
We describe the rate and spectrum of spontaneous mutations for the social amoeba Dictyostelium discoideum, a key model organism in molecular, cellular, evolutionary and developmental biology. Whole-genome sequencing of 37 mutation accumulation lines of D.
Sibel Kucukyildirim   +8 more
doaj   +1 more source

Visualization of c-di-GMP in multicellular Dictyostelium stages

open access: yesFrontiers in Cell and Developmental Biology, 2023
The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes.
Hayato Ide   +3 more
doaj   +1 more source

Chemotaxis of Dictyostelium discoideum: collective oscillation of cellular contacts. [PDF]

open access: yesPLoS ONE, 2013
Chemotactic responses of Dictyostelium discoideum cells to periodic self-generated signals of extracellular cAMP comprise a large number of intricate morphological changes on different length scales.
Edith Schäfer   +7 more
doaj   +1 more source

Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses

open access: yesFrontiers in Immunology, 2018
The soil-dwelling social amoeba Dictyostelium discoideum feeds on bacteria. Each meal is a potential infection because some bacteria have evolved mechanisms to resist predation. To survive such a hostile environment, D.
J. Dunn   +7 more
semanticscholar   +1 more source

A Heat Shock Protein 48 (HSP48) Biomolecular Condensate Is Induced during Dictyostelium discoideum Development

open access: yesmSphere, 2019
The social amoeba Dictyostelium discoideum’s proteome contains a vast array of simple sequence repeats, providing a unique model to investigate proteostasis. Upon conditions of cellular stress, D.
Stephanie Santarriaga   +3 more
doaj   +1 more source

Role of epigenetics in unicellular to multicellular transition in Dictyostelium

open access: yesGenome Biology, 2021
Background The evolution of multicellularity is a critical event that remains incompletely understood. We use the social amoeba, Dictyostelium discoideum, one of the rare organisms that readily transits back and forth between both unicellular and ...
Simon Yuan Wang   +10 more
doaj   +1 more source

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