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Dictyostelium discoideum: A Model System for Neurological Disorders
Background: The incidence of neurological disorders is increasing due to population growth and extended life expectancy. Despite advances in the understanding of these disorders, curative strategies for treatment have not yet eventuated. In part, this is
Claire Louise Storey+3 more
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Analysis of optical density wave propagation and cell movement in the cellular slime mould Dictyostelium discoideum [PDF]
We have studied optical density wave propagation during aggregation of the cellular slime mould Dictyostelium discoideum in a quantitative manner by digital image analysis.
Siegert, Florian, Weijer, Cornelis J.
core +1 more source
Spontaneous center formation in Dictyostelium discoideum [PDF]
AbstractDictyostelium discoideum (D.d.) is a widely studied amoeba due to its capabilities of development, survival, and self-organization. During aggregation it produces and relays a chemical signal (cAMP) which shows spirals and target centers. Nevertheless, the natural emergence of these structures is still not well understood.
Estefania Vidal-Henriquez, Azam Gholami
openaire +4 more sources
Initiation of multicellular differentiation in Dictyostelium discoideum is regulated by coronin A
Multicellular development of Dictyostelium is induced by starvation and is crucial for its long-term survival. Coronin A mediates the transition from growth to development of the cells and initiates the cAMP-dependent relay by regulating the response to ...
Adrien F. Vinet+6 more
semanticscholar +1 more source
Nucleases: From Primitive Immune Defenders to Modern Biotechnology Tools
The evolution of nucleases is a remarkable journey, starting as primitive bacterial defenders against bacteriophages. Over time, nucleases have adapted to specialised roles within the immune systems of all forms of life, culminating in humans, where DNases and RNases serve as key components of the immune system.
Frank J. Hernandez
wiley +1 more source
Se determinaron los parámetros cinéticos y el efecto de fructosa 2,6-bifosfato sobre fosfofructokinasa (PFK) y fructosa 1,6-bifosfatasa (FBP-asa) parcialmente purificadas, obtenidas de homogenados de células vegetativas y diferenciadas de Dictyostelium ...
Ospina G. Blanca Lucía
doaj
CHROMOSOME REARRANGEMENTS IN DICTYOSTELIUM DISCOIDEUM [PDF]
ABSTRACT A tandem duplication (D350(III,III)) of the whiB to radB interval of linkage group III has been characterized. The gene order on the duplication-bearing chromosome is: centromere, whiB500, radB+, whiB+, radB24, bsgA5, acrC4. Slow-growing, duplication-bearing strains (yellow-spored, radiation-resistant) produced four classes of ...
Keith L. Williams+2 more
openaire +3 more sources
Growth of myxameobae of the cellular slime mould Dictyostelium discoideum in axenic culture.
1. A simple axenic medium suitable for the growth of the myxamoebae of a strain of the cellular slime mould Dictyostelium discoideum is described. 2. Procedures suitable for the growth of this strain in liquid and on solid media are described.
D. Watts, J. Ashworth
semanticscholar +1 more source
Abstract Phenylalanine ammonia lyase (PAL) enzymes have been extensively exploited to produce differently substituted arylalanine analogues, but their use in the stereoselective synthesis of aliphatic fatty amino acids has never been addressed. In this work, a two‐step hydroamination‐hydrodesulfurisation process has been investigated for the production
Celeste Nobbio+5 more
wiley +1 more source
The Elmo family forms an ancient group of actin-regulating proteins
The Elmo protein family members are important mediators of small G protein activity, regulating actin-mediated processes such as chemotaxis and engulfment.
Joseph A. Brzostowski+4 more
doaj +1 more source