Results 111 to 120 of about 46,917 (300)

Biochemical characterization of cardiac α‐actin mutations A21V and D26N implicated in hypertrophic cardiomyopathy

Cytoskeleton, Volume 81, Issue 12, Page 815-831, December 2024.
Abstract Familial hypertrophic cardiomyopathy (HCM) affects .2% of the world's population and is inherited in an autosomal dominant manner. Mutations in cardiac α‐actin are the cause in 1%–5% of all observed cases. Here, we describe the recombinant production, purification, and characterization of the HCM‐linked cardiac α‐actin variants p.A21V and p ...
Johannes N. Greve, Frederic V. Schwäbe, Manuel H. Taft, Dietmar J. Manstein   +3 more
wiley   +1 more source

No Evidence for a Negative Effect of Realism When Learning About a Process Despite an Increase in Cognitive Load

Applied Cognitive Psychology, Volume 38, Issue 6, November/December 2024.
ABSTRACT Realistic visualizations have been found to enhance the learning of object shapes, but regarding the learning of processes, the effects of realism are largely unclear. Previous findings indicate that realism can induce a higher level of extraneous cognitive load compared with schematics and that details are attention‐consuming.
Alexander Skulmowski
wiley   +1 more source

Conditional expression explains molecular evolution of social genes in a microbe

Nature Communications, 2019
Genetic diversity in social genes is expected to be shaped by conflict. Here, the authors show that in Dictyostelium discoideum, social genes in fact exhibit diversification patterns consistent with relaxed purifying selection, likely due to their ...
Janaina Lima de Oliveira, Atahualpa Castillo Morales, Balint Stewart, Nicole Gruenheit, Jennifer Engelmoer, Suzanne Battom Brown, Reinaldo A. de Brito, Laurence D. Hurst, Araxi O. Urrutia, Christopher R. L. Thompson, Jason B. Wolf   +10 more
doaj   +1 more source

Statistical inference of the mechanisms driving collective cell movement [PDF]

, 2017
Numerous biological processes, many impacting on human health, rely on collective cell movement. We develop nine candidate models, based on advection-diffusion partial differential equations, to describe various alternative mechanisms that may drive ...
Aderhold, Agostinelli, Bernstein, Bishop, Carnell, Coburn, Cressie, De Wit, Deisboeck, Donà, Eitle, Ershad, Fleming, Fortin, Friel, Gelman, Gelman, Geweke, Girolami, Green, Haario, Hillen, Hu, Insall, Jaiswal, Kakebeeke, Kalimuthu, Keating, Keller, Keller, Kooperberg, Laevsky, Loomis, Macdonald, Majumdar, McDonough, Moorcroft, Muinonen-Martin, Neilson, R Core Team, Rue, Scherber, Schiesser, Schwarz, Sibert, Soetaert, Soetaert, Spiegelhalter, Stone, Tweedy, Tweedy, Varnum, Venkiteswaran, Watanabe, Wikle, Wyckoff, Xun, Zlatev, Zoppou   +58 more
core   +1 more source

ABC Transporters in Dictyostelium discoideum Development

PLoS ONE, 2013
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients.
Adam Kuspa, Blaz Zupan, Blaz Zupan, Marko Toplak, Gad Shaulsky, Edward Roshan Miranda, Olga Zhuchenko, Balaji Santhanam   +7 more
openaire   +7 more sources

Comparative structural study on axonemal and cytoplasmic dyneins

Cytoskeleton, Volume 81, Issue 11, Page 681-690, November 2024.
Abstract Axonemal dyneins are the driving force of motile cilia, while cytoplasmic dyneins play an essential role in minus‐end oriented intracellular transport. Their molecular structure is indispensable for an understanding of the molecular mechanism of ciliary beating and cargo transport. After some initial structural analysis of cytoplasmic dyneins,
Noemi Zimmermann, Takashi Ishikawa
wiley   +1 more source

The lipid composition and membrane fluidity of Dictyostelium discoideum plasma membranes at various stages during differentiation.

Journal of Lipid Research, 1980
There are only minor changes in the amounts of the major lipid constituents of Dictyostelium discoideum plasma membranes during the early stages in the differentiation of this organism.
G Weeks, F G Herring
doaj  

Assets of the non-pathogenic microorganism Dictyostelium discoideum as a model for the study of eukaryotic extracellular vesicles [v1; ref status: indexed, http://f1000r.es/pa]

F1000Research, 2013
Dictyostelium discoideum microvesicles have recently been presented as a valuable model for eukaryotic extracellular vesicles. Here, the advantages of D.
Irène Tatischeff
doaj   +1 more source

Fluctuation theorem applied to Dictyostelium discoideum system [PDF]

, 2007
In this paper, we analyze the electrotactic movement of Dictyostelium discoideum from the viewpoint of non-equilibrium statistical mechanics. Because we can observe fluctuating behavior of cellular trajectories, we analyze the probability distribution of
Ciliberto S., Crisanti A., Feitosa K., Hayashi K., Miyoshi H., Sato M. J., Selmeczi D., Uchida K. S., Wang G. M., Zhao M.   +9 more
core   +1 more source

Dictyostelium discoideum, una ameba peculiar

Treballs de la Societat Catalana de Biologia, 2011
Peer ...
Galardi-Castilla, María, Sastre, Leandro   +1 more
openaire   +4 more sources