Results 21 to 30 of about 47,596 (285)

Convergent pairs of highly transcribed genes restrict chromatin looping in Dictyostelium discoideum. [PDF]

Nucleic Acids Res
Zhegalova IV, Ulianov SV, Galitsyna AA, Pletenev IA, Tsoy OV, Luzhin AV, Vasiluev PA, Bulavko ES, Ivankov DN, Gavrilov AA, Khrameeva EE, Gelfand MS, Razin SV.   +12 more
europepmc   +2 more sources

Insights on Microsatellite Characteristics, Evolution, and Function From the Social Amoeba Dictyostelium discoideum

Frontiers in Neuroscience, 2022
Microsatellites are repetitive sequences commonly found in the genomes of higher organisms. These repetitive sequences are prone to expansion or contraction, and when microsatellite expansion occurs in the regulatory or coding regions of genes this can ...
Felicia N. Williams, K. Matthew Scaglione, K. Matthew Scaglione, K. Matthew Scaglione   +3 more
doaj   +1 more source

The proppin Bcas3 and its interactor KinkyA localize to the early phagophore and regulate autophagy [PDF]

, 2021
To resolve the signaling mechanisms that mediate the starvation-induced processes of Dictyostelium sporulation and encystation, we performed insertional mutagenesis on cells harboring an mRFP-tagged spore gene.
Schaap, Pauline, Yamada, Yoko
core   +2 more sources

A recombinant antibody toolbox for Dictyostelium discoideum

BMC Research Notes, 2020
Objective The amoeba Dictyostelium discoideum has been a valuable model organism to study numerous facets of eukaryotic cell biology, such as cell motility, cell adhesion, macropinocytosis and phagocytosis, host–pathogen interactions and multicellular ...
Wanessa C. Lima, Philippe Hammel, Pierre Cosson   +2 more
doaj   +1 more source

A RabGAP regulates life-cycle duration via trimeric G-protein cascades in Dictyostelium discoideum. [PDF]

PLoS ONE, 2013
BACKGROUND: The life-cycle of cellular slime molds comprises chronobiologically regulated processes. During the growth phase, the amoeboid cells proliferate at a definite rate.
Hidekazu Kuwayama, Yukihiro Miyanaga, Hideko Urushihara, Masahiro Ueda   +3 more
doaj   +1 more source

Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of Dictyostelium discoideum

G3: Genes, Genomes, Genetics, 2020
We describe the rate and spectrum of spontaneous mutations for the social amoeba Dictyostelium discoideum, a key model organism in molecular, cellular, evolutionary and developmental biology. Whole-genome sequencing of 37 mutation accumulation lines of D.
Sibel Kucukyildirim, Megan Behringer, Way Sung, Debra A. Brock, Thomas G. Doak, Hatice Mergen, David C. Queller, Joan E. Strassmann, Michael Lynch   +8 more
doaj   +1 more source

Identification of the protein kinases Pyk3 and Phg2 as regulators of the STATc-mediated response to hyperosmolarity [PDF]

, 2014
Cellular adaptation to changes in environmental osmolarity is crucial for cell survival. In Dictyostelium, STATc is a key regulator of the transcriptional response to hyperosmotic stress. Its phosphorylation and consequent activation is controlled by two
A Kortholt, A Kortholt, AA Noegel, Adrian John Harwood, BK Gilsbach, C Blanc, Christoph S. Clemen, CR Thompson, DE Levy, H Kiu, H Kuwayama, H Towbin, J Faix, J Langenick, J Na, Jeffrey G. Williams, Jianbo Na, JM Goldberg, K Adler, KL Williams, L Gebbie, Linh Hai Vu, Ludwig Eichinger, M Brink, M Fukuzawa, M Gamper, MR Lee, NS Lee, P Farbrother, P Gatsios, R Kang, RH Insall, T Araki, T Araki, T Araki, T Araki, Tsuyoshi Araki, UK Laemmli   +37 more
core   +10 more sources

Visualization of c-di-GMP in multicellular Dictyostelium stages

Frontiers in Cell and Developmental Biology, 2023
The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes.
Hayato Ide, Yukihisa Hayashida, Yusuke V. Morimoto, Yusuke V. Morimoto   +3 more
doaj   +1 more source

A Heat Shock Protein 48 (HSP48) Biomolecular Condensate Is Induced during Dictyostelium discoideum Development

mSphere, 2019
The social amoeba Dictyostelium discoideum’s proteome contains a vast array of simple sequence repeats, providing a unique model to investigate proteostasis. Upon conditions of cellular stress, D.
Stephanie Santarriaga, Alicia Fikejs, Jamie Scaglione, K. Matthew Scaglione   +3 more
doaj   +1 more source

Role of epigenetics in unicellular to multicellular transition in Dictyostelium

Genome Biology, 2021
Background The evolution of multicellularity is a critical event that remains incompletely understood. We use the social amoeba, Dictyostelium discoideum, one of the rare organisms that readily transits back and forth between both unicellular and ...
Simon Yuan Wang, Elizabeth Ann Pollina, I-Hao Wang, Lindsay Kristina Pino, Henry L. Bushnell, Ken Takashima, Colette Fritsche, George Sabin, Benjamin Aaron Garcia, Paul Lieberman Greer, Eric Lieberman Greer   +10 more
doaj   +1 more source