Results 31 to 40 of about 46,917 (300)
Recent Insights into NCL Protein Function Using the Model Organism Dictyostelium discoideum
The neuronal ceroid lipofuscinoses (NCLs) are a group of devastating neurological disorders that have a global distribution and affect people of all ages.
Meagan D. McLaren+2 more
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Models of Dictyostelium discoideum Aggregation [PDF]
Since its discovery in the 1940’s, the life cycle of the cellular slime mould Dictyostelium discoideum has attracted the interest of developmental biologists. It involves a relatively simple transition from unicellular to multicellular organization. Briefly, amoebae feed on bacteria in the soil and divide.
Dallon, J+6 more
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Chemical compounds from Dictyostelium discoideum repel a plant-parasitic nematode and can protect roots. [PDF]
Slime mold species in the genus Dictyostelium are considered to have a close relationship with non-parasitic nematodes; they are sympatric in soils and can exhibit interspecific competition for food. We investigated whether this relationship extends to a
Yumiko F Saito+4 more
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The contractile proteins of dictyostelium discoideum [PDF]
AbstractWe have purified actin and my osin‐like proteins from amoebae of Dictyostelium discoideum. These proteins are very similar in their physical and enzymatic properties to muscle actin and myosin. Most importantly, they form thin and thick filaments, respectively, and Dictyostelium actin activates Dictyostelium myosin ATPase activity.
James A. Spudich, Margaret Clarke
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Cooperation and conflict in the social amoeba Dictyostelium discoideum.
The social amoeba Dictyostelium discoideum has provided considerable insight into the evolution of cooperation and conflict. Under starvation, D. discoideum amoebas cooperate to form a fruiting body comprised of hardy spores atop a stalk.
J. Medina+4 more
semanticscholar +1 more source
Background Anandamide (Arachidonoyl ethanolamide) is a potent bioactive lipid studied extensively in humans, which regulates several neurobehavioral processes including pain, feeding and memory.
Neelamegan Dhamodharan+3 more
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Human macrophages and the eukaryotic microbe Dictyostelium discoideum ingest bacteria by phagocytosis, and then kill the ingested bacteria. Some pathogenic bacteria secrete linear chains of phosphate residues (polyphosphate; polyP), and the polyP ...
Ryan J. Rahman+5 more
doaj +1 more source
Profilin isoforms in Dictyostelium discoideum
Eukaryotic cells contain a large number of actin binding proteins of different functions, locations and concentrations. They bind either to monomeric actin (G-actin) or to actin filaments (F-actin) and thus regulate the dynamic rearrangement of the actin cytoskeleton.
Jayabalan M. Joseph+8 more
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Alkaline Phosphatase in Dictyostelium discoideum [PDF]
Several phosphatases have been demonstrated in Dictyostelium discoideum. The alkaline phosphatase, pH optimum 9·0, is a 5′-nucleotidase, attacking adenosine monophosphate and deoxyadenosine monophosphate, but catalyses also hydrolysis of p-nitrophenyl phosphate.
Kerstin Gezelius, Barbara E. Wright
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Dictyostelium has a mature technology for molecular-genetic manipulation based around transfection using several different selectable markers, marker re-cycling, homologous recombination and insertional mutagenesis, all supported by a well-annotated ...
Peggy I. Paschke+9 more
semanticscholar +1 more source