Results 81 to 90 of about 980 (147)

Table_1_Novel computational and drug design strategies for inhibition of monkeypox virus and Babesia microti: molecular docking, molecular dynamic simulation and drug design approach by natural compounds.DOCX

, 2023
BackgroundThe alarming increase in tick-borne pathogens such as human Babesia microti is an existential threat to global public health. It is a protozoan parasitic infection transmitted by numerous species of the genus Babesia.
Saddam Hossain (9365612), Nobendu Mukerjee (12152507), Shopnil Akash (13866545), Hiba-Allah Nafidi (16453347), Yousef A. Bin Jardan (8535450), Mohammed Bourhia (11228466), Sajjat Mahmood (16614408), Showkat Ahmad Mir (12303653), Amare Mekonnen (16614414), Md. Rezaul Islam (16614411), Binata Nayak (9944905)   +10 more
core   +1 more source

Protective effect of Ecklonia cava on UVB-induced oxidative stress: in vitro and in vivo zebrafish model

, 2010
Chronic exposure of the skin to ultraviolet B (UVB) radiation induces oxidative stress, which plays a crucial role in the induction of skin aging. In this study, potential protective effect of extracts of six species of brown seaweeds on UVB radiation ...
Seok-Chun Ko, Seon-Heui Cha, Soo-Jin Heo, Jeon, You-Jin, Cha, Seon-Heui, Ko, Seok-Chun, Sung-Myung Kang, Seung-Hong Lee, Kang, Sung-Myung, Lee, Seung-Hong, You-Jin Jeon, Heo, Soo-Jin   +11 more
core   +1 more source

Isolation and Structural Determination of Two Novel Phlorotannins from the Brown Alga Ecklonia kurome Okamura, and Their Radical Scavenging Activities

Marine Drugs, 2013
Two novel phlorotannins with a molecular weight of 974, temporarily named 974-A and 974-B, were isolated from the polyphenol powder prepared from the edible marine brown alga Ecklonia kurome Okamura, and their chemical structures were determined by ...
Yuko Cho, Keiichi Konoki, Hisatomi Ito, Haruhiko Toyohara, Yi-Chin Lin, Shinya Segawa, Sawako Kondo, Mari Yotsu-Yamashita, Takafumi Uchida   +8 more
doaj   +1 more source

Table_2_Novel computational and drug design strategies for inhibition of monkeypox virus and Babesia microti: molecular docking, molecular dynamic simulation and drug design approach by natural compounds.DOCX

, 2023
BackgroundThe alarming increase in tick-borne pathogens such as human Babesia microti is an existential threat to global public health. It is a protozoan parasitic infection transmitted by numerous species of the genus Babesia.
Saddam Hossain (9365612), Nobendu Mukerjee (12152507), Shopnil Akash (13866545), Hiba-Allah Nafidi (16453347), Yousef A. Bin Jardan (8535450), Mohammed Bourhia (11228466), Sajjat Mahmood (16614408), Showkat Ahmad Mir (12303653), Amare Mekonnen (16614414), Md. Rezaul Islam (16614411), Binata Nayak (9944905)   +10 more
core   +1 more source

Seapolynol and Dieckol Improve Insulin Sensitivity through the Regulation of the PI3K Pathway in C57BL/KsJ-db/db Mice

, 2020
Ecklonia cava, a brown alga native to the seas of Korea and Japan, contains biologically active polyphenols. Seapolynol (SN) is a polyphenol mixture derived from Ecklonia cava, and dieckol (DK) is a major compound of SN.
Hui-Jeon Jeon, Eun-Jeong Koh, Jia Choi, Boo-Yong Lee, Hyeon-Son Choi, " Seapolynol, Dieckol, Kye-Yoon Yoon, Kui-Jin Kim   +8 more
core  

Neuroprotective mechanisms of dieckol against glutamate toxicity through reactive oxygen species scavenging and nuclear factor-like 2/heme oxygenase-1 pathway

, 2019
Glutamate toxicity-mediated mitochondrial dysfunction and neuronal cell death are involved in the pathogenesis of several neurodegenerative diseases as well as acute brain ischemia/stroke.
Amarsanaa, K, Joo Min Park, Rhim, JK, Cui, YJ, Lee, JH, Kwon, JM, Kim, SH, Jung, SC, Eun, SY   +8 more
core   +1 more source

에클로니아 카바에서 추출한 플로로퓨코퓨로엑콜A와 디엑콜의 쥐 모델에서의 소음성 난청 보호 효과

, 2021
학위논문(석사) -- 서울대학교대학원 : 의과대학 의학과, 2021.8. 박무균.난청의 가장 흔한 원인 중 하나는 소음이다. 20세와 69세 사이 미국인들 중 약 31.1%가 소음과 연관된 고음 난청이 있다. 또한 반복적인 소음 노출은 노화와 관련된 난청을 가속시킬 수 있다. 감태에서 추출된 폴리페놀류 성분인 디엑콜과 플로로푸코푸로엑콜 A는 강력한 항산화제들이다.
우현준
core  

Antioxidant Activity of Various Solvent Fractions from Edible Brown Alga, Eisenia bicyclis and Its Active Compounds

, 2013
In this study, we aimed to elucidate the antioxidant capacity of Eisenia bicyclis and evaluated its antioxidant activity using various assay systems such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, 2,2-azino-bis (3-ethylbenzthiazoline-6 ...
Kim, Choong-Gon, Kim, Tae-Wan, Park, Nyun-Ho, Kwon, Tae-Hyung   +3 more
core   +1 more source

Molecular Docking and Molecular Dynamics Analysis to Identify Marine‑Derived Compounds as Androgen Receptor Inhibitors [PDF]

Prostate cancer (PCa), as a leading cancer type among males, is a major global health issue. The pathogenesis of cancer progression is considered to be related to the androgen receptor (AR), which makes it a promising therapeutic target.
Bahelanbieke, Dina
core   +1 more source

Plant polyphenols as broad-spectrum antivirals: Comprehensive potency profiling against major virus families

Journal of Advanced Biotechnology and Experimental Therapeutics
Plant polyphenols are promising candidates for broad-spectrum antiviral development, but their comparative potency and selectivity across virus families remain poorly characterized.
Fredmoore Legaspi Orosco
doaj   +1 more source