Results 141 to 150 of about 81,193 (228)

Five Decades of Dispute: A Triptych. E. J. Corey

The Chemical Record, EarlyView.
In his 2004 Priestley Medal address, E. J. Corey stated, “On May 4, 1964, I suggested to my colleague R. B. Woodward a simple explanation involving the symmetry of the perturbed (HOMO) molecular orbitals for the stereoselective cyclobutene/1,3‐butadiene and 1,3,5‐hexatriene/cyclohexadiene conversions that provided the basis for the further development ...
Jeffrey I. Seeman
wiley   +1 more source

Five Decades of Dispute: A Triptych. Roald Hoffmann

The Chemical Record, EarlyView.
This article examines the historical Corey–Woodward controversy through Roald Hoffmann's personal perspective, completing a triptych on the prolonged dispute. Drawing on archival records, contemporaneous correspondence, and extensive interviews, it reconstructs Hoffmann's interactions with Corey and Woodward from the 1960s onward.
Jeffrey I. Seeman
wiley   +1 more source

Recent Advances in the Synthesis of Heterocycles via Diels-Alder Reactions on Chromone Cores. [PDF]

ACS Omega
Heredia-Moya J.
europepmc   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

Concerted Bond Formation in Diels-Alder Reactions: A Configuration Analysis. [PDF]

ACS Omega
Sakata K, Yano T, Ikeda N, Yoshikawa T.
europepmc   +1 more source

Metal‐Catalyzed Benzannulation: Recent Advances in Catalyst Design, Mechanistic Insights, and Aromatic Framework Construction

The Chemical Record, EarlyView.
This review offers a contemporary overview of metal‐catalyzed benzannulation (2018–present) encompassing transition, main‐group, post‐transition, and rare‐earth‐metal catalysts. It systematically highlights catalyst design, mechanistic insights, stereo‐ and regioselectivity, and synthetic applications toward aromatic and heteroaromatic scaffolds, while
Sana Jamshaid, Divya Shrestha, Raju S. Thombal, Jeung Gon Kim, Kim Seong Cheol, Yong Rok Lee   +5 more
wiley   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Repurposing Diels-Alder Chemistry to Access Low-Strain Monomers for Chemically Recyclable ROMP Polymers. [PDF]

ACS Macro Lett
Ibrahim T, Rahman MA, Kaczynski M, Cardella C, Sun H.   +4 more
europepmc   +1 more source

Diels-Alder Cycloaddition in Medicinal Chemistry

, 2016
: Diels-Alder reactions have emerged as highly powerful transformations for the generation of structurally complex polycyclic scaffolds essentially due to their associated rapidity and atom-economy.
Larraufie, Marie-Helene, Bouchez, Laure, Rusch, Marion   +2 more
core  

Brief encounters and lasting impressions—How target protein half‐life affects reactive metabolite signaling

The FEBS Journal, EarlyView.
Lipid‐derived reactive electrophile molecules (REMs) are generated from fatty acids through lipoxygenase or cyclooxygenase‐assisted catalysis, or free radical‐induced lipid peroxidation events. REMs so‐produced covalently modify nearby protein‐cysteines, and in the case of ‘first responder’ proteins, can trigger gain‐of‐function signaling with context ...
Marcus J. C. Long, Lorna Birkby, Yimon Aye   +2 more
wiley   +1 more source