Results 181 to 190 of about 81,193 (228)

Bioorthogonal Chemistry in Neurobiology: From Imaging to Proteomics

open access: yesChemBioChem, Volume 27, Issue 20, 28 October 2026.
This review highlights emerging strategies for labeling neuronal proteins, enabling visualization and quantitative analysis of their expression, localization, and dynamics. By combining genetic code expansion (GCE), metabolic labeling, and click chemistry‐based labeling, these approaches provide powerful routes to study proteins in specific cells and ...
Neil Taylor   +2 more
wiley   +1 more source

Supramolecular Mechanophore Additives Enable Mechanochromic Hydrogels

open access: yesAngewandte Chemie, Volume 138, Issue 44, 26 October 2026.
A supramolecular loop‐forming mechanophore featuring a quencher and an emitter is incorporated as a water‐soluble macromolecular additive into hydrogels. In the stress‐free state, intramolecular charge‐transfer interactions fold the loop and quench fluorescence.
Iulia Scarlat   +2 more
wiley   +2 more sources

Sustainable Routes Toward Amino Acid‐Based Surfactants: Borrowing Hydrogen Catalysis and Beyond

open access: yesChemSusChem, Volume 19, Issue 20, 28 October 2026.
This perspective examines how amino acid‐based surfactants become more sustainable only when molecular architecture is matched to an appropriate synthetic disconnection. Borrowing Hydrogen catalysis provides a central route to N‐alkylated derivatives, while enzymatic, biosynthetic, and renewable‐platform strategies complement it.
Maximilian Fellert, Ben L. Feringa
wiley   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu   +2 more
wiley   +1 more source

Emergent Atropisomerism Through Diels–Alder Reactions of Vinylallenes

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.
Cycloaddition‐induced geometric reorganization transforms achiral vinylallenes into atropisomeric styrenes. Conformational flexibility governs atropisomerization barriers, thermodynamic preferences, and configurational stability. Atropisomeric styrenes remain comparatively underdeveloped because configurational stability about the C(sp2)C(sp2) bond is
Kusum Sai   +3 more
wiley   +1 more source

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