Molybdooxaziridine Catalysis: Synthesis of α‐Hydroxysulfones From Styrenes Through an ATRA Process
European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.This work has discovered that molybdooxaziridine catalysts promote the hydroxysulfonation of substituted α‐methyl‐styrenes using N‐Ts‐hydroxylamine as the nitrogen source. An atom‐transfer‐radical‐addition mechanism involving the stepwise addition of Ts and hydroxy radicals takes place.
Alyssa N. Singer, Gustavo Moura‐Letts
wiley +1 more source
Cerium(III) immobilized on the functionalized halloysite as a highly efficient catalyst for aza-Diels-Alder reaction. [PDF]
Sci RepHosseini A +4 more
europepmc +1 more source
Angewandte Chemie International Edition, Volume 65, Issue 43, 19 October 2026.Renewable guaiacols are rapidly oxidized by phenyliodine(III)diacetate to masked ortho‐quinones, giving a new class of monomers that undergo selective Michael‐type polyaddition with multithiols to from thiol‐guaiacol connectivity‐bearing polymers. The activation applies to discrete monomers and directly to lignin, enabling two‐component adhesives that ...
Dominik P. Hoch +7 more
wiley +1 more source
Computational Investigation of a CO<sub>2</sub> Conversion Strategy via Diels-Alder Reaction in a Carbon Capture Solvent. [PDF]
ACS OmegaZhang D +6 more
europepmc +1 more source
Toward Ideal Proximity‐Driven Reactions in Chemical Biology
ChemBioChem, Volume 27, Issue 19, 14 October 2026.Building on established principles of molecular templation, this perspective explores how molecular recognition can control chemical reactivity in space and time and outlines the design principles of an ideal proximity‐driven reaction for chemical biology.
Dominik Schauenburg
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy +7 more
wiley +2 more sources
Dual Feedstock Upcycling of α-Methylstyrene-Doped Poly(methyl methacrylate) and Biomass via the Telescope of Depolymerization and Diels-Alder Reaction. [PDF]
Org LettZhang R, Chin MT, Diao T.
europepmc +1 more source
A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids
Chemistry – A European Journal, Volume 32, Issue 38, 13 October 2026.This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci +8 more
wiley +1 more source
Flavin Catalysts in Organic Synthesis
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley +2 more sources
Analysis of the Reactivity of Z-2-Ar-1-EWG-1-Nitroethene Molecular Segment in the Hetero Diels-Alder Reaction: Experimental and MEDT Quantum Chemical Study. [PDF]
MoleculesWoliński P +4 more
europepmc +1 more source