Results 191 to 200 of about 7,607,880 (287)

Systematic Optimization of an SLE‐DAPTAD LC–MS/MS Workflow for Simultaneous Quantification of Low‐Abundance Vitamin D3 Metabolites in Plasma

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 20, 30 October 2026.
ABSTRACT Rationale Liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis of vitamin D3 metabolites is analytically challenging because these compounds are structurally similar, strongly matrix‐associated, and have poor ionization efficiency.
Marzieh Amirmostofian   +3 more
wiley   +1 more source

Bioorthogonal Chemistry in Neurobiology: From Imaging to Proteomics

open access: yesChemBioChem, Volume 27, Issue 20, 28 October 2026.
This review highlights emerging strategies for labeling neuronal proteins, enabling visualization and quantitative analysis of their expression, localization, and dynamics. By combining genetic code expansion (GCE), metabolic labeling, and click chemistry‐based labeling, these approaches provide powerful routes to study proteins in specific cells and ...
Neil Taylor   +2 more
wiley   +1 more source

Supramolecular Mechanophore Additives Enable Mechanochromic Hydrogels

open access: yesAngewandte Chemie, Volume 138, Issue 44, 26 October 2026.
A supramolecular loop‐forming mechanophore featuring a quencher and an emitter is incorporated as a water‐soluble macromolecular additive into hydrogels. In the stress‐free state, intramolecular charge‐transfer interactions fold the loop and quench fluorescence.
Iulia Scarlat   +2 more
wiley   +2 more sources

Sustainable Routes Toward Amino Acid‐Based Surfactants: Borrowing Hydrogen Catalysis and Beyond

open access: yesChemSusChem, Volume 19, Issue 20, 28 October 2026.
This perspective examines how amino acid‐based surfactants become more sustainable only when molecular architecture is matched to an appropriate synthetic disconnection. Borrowing Hydrogen catalysis provides a central route to N‐alkylated derivatives, while enzymatic, biosynthetic, and renewable‐platform strategies complement it.
Maximilian Fellert, Ben L. Feringa
wiley   +1 more source

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