Results 181 to 190 of about 7,607,880 (287)
Endophytic fungi encode abundant cryptic biosynthetic gene clusters that remain largely silent under conventional cultivation. This review highlights how genome mining, multi‐omics, and cluster activation strategies bridge the BGC‐to‐metabolite gap, enabling the discovery of structurally diverse antibacterial natural products with activity against ...
Farkhod Eshboev +8 more
wiley +1 more source
Reactivity and Stereoselectivity in the Inverse-Electron-Demand Diels-Alder Reaction of 1-Aza-1,3-Butadiene. [PDF]
Sakata K, Go Y, Yoshikawa T.
europepmc +1 more source
ABSTRACT High‐resolution mass spectrometry (HRMS) coupled with ultra‐high‐performance liquid chromatography (UHPLC) enables rapid characterization of complex polyphenolic constituents in medicinal plants. Mansoa hirsuta (Bignoniaceae), a neotropical liana traditionally used to treat infectious diseases, remains poorly characterized chemically.
Adriana Cotta Cardoso Reis +6 more
wiley +1 more source
Catalytic Enantioselective Diels-Alder Reaction of Dienes with Acyclic and α,β- and β,β-Disubstituted Enones. [PDF]
Samsonowicz-Górski J +7 more
europepmc +1 more source
Effect of Solvent Polarity on the Anionic Polymerization of (Z)‐1‐Phenyl[3]Dendralene
Anionic polymerization of (Z)‐1‐phenyl[3]dendralene in toluene afforded a polymer with the expected molecular weight and a narrow molecular weight distribution under appropriate polymerization conditions. However, broadening of the molecular weight distribution and gelation of the polymerization product occur when the polymerization mixture is allowed ...
Haruto Tanaka +2 more
wiley +1 more source
Zwitterionic Pathway in the Diels-Alder Reaction: Solvent and Substituent Effects from ωB97XD/6-311G(d) Calculations. [PDF]
Łapczuk A.
europepmc +1 more source
Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies
Graphical overview of targeted protein degradation: mechanisms, molecular determinants, delivery strategies, and therapeutic development. This graphical abstract summarizes the major degradation pathways involved in targeted protein degradation, including the ubiquitin–proteasome system, endocytosis–lysosome pathway, and autophagy‐dependent degradation.
Huaijuan Guo +8 more
wiley +1 more source
A Straightforward Approach Towards Phosphadecalones by Microwave-Assisted Diels-Alder Reaction. [PDF]
Łastawiecka E +2 more
europepmc +1 more source
An Investigations‐Based Undergraduate Computational Chemistry Course
Chemistry 164 is a hands‐on undergraduate computational chemistry course at Pomona College using publicly available materials (https://tinyurl.com/PomonaChem164) and structured around literature‐based investigations of organic structure and reactivity, isotope effects, NMR parameters, and organometallic systems.
Daniel J. O'Leary
wiley +1 more source

