Results 181 to 190 of about 7,607,880 (287)

Biosynthetic Pathways and Regulation of Antibacterial Compounds From Endophytic Fungi: From Chemistry to Genomics and Biotechnology

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Endophytic fungi encode abundant cryptic biosynthetic gene clusters that remain largely silent under conventional cultivation. This review highlights how genome mining, multi‐omics, and cluster activation strategies bridge the BGC‐to‐metabolite gap, enabling the discovery of structurally diverse antibacterial natural products with activity against ...
Farkhod Eshboev   +8 more
wiley   +1 more source

UHPLC‐DAD‐HRMS2 Characterization of Novel Dihydrochalcone Conjugates From the Antiviral Mansoa hirsuta Extracts: Diagnostic Fragmentation Pathways and Dereplication of Oligomeric Polyphenols

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 11, November 2026.
ABSTRACT High‐resolution mass spectrometry (HRMS) coupled with ultra‐high‐performance liquid chromatography (UHPLC) enables rapid characterization of complex polyphenolic constituents in medicinal plants. Mansoa hirsuta (Bignoniaceae), a neotropical liana traditionally used to treat infectious diseases, remains poorly characterized chemically.
Adriana Cotta Cardoso Reis   +6 more
wiley   +1 more source

Catalytic Enantioselective Diels-Alder Reaction of Dienes with Acyclic and α,β- and β,β-Disubstituted Enones. [PDF]

open access: yesJ Am Chem Soc
Samsonowicz-Górski J   +7 more
europepmc   +1 more source

Effect of Solvent Polarity on the Anionic Polymerization of (Z)‐1‐Phenyl[3]Dendralene

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 21, 13 November 2026.
Anionic polymerization of (Z)‐1‐phenyl[3]dendralene in toluene afforded a polymer with the expected molecular weight and a narrow molecular weight distribution under appropriate polymerization conditions. However, broadening of the molecular weight distribution and gelation of the polymerization product occur when the polymerization mixture is allowed ...
Haruto Tanaka   +2 more
wiley   +1 more source

Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Graphical overview of targeted protein degradation: mechanisms, molecular determinants, delivery strategies, and therapeutic development. This graphical abstract summarizes the major degradation pathways involved in targeted protein degradation, including the ubiquitin–proteasome system, endocytosis–lysosome pathway, and autophagy‐dependent degradation.
Huaijuan Guo   +8 more
wiley   +1 more source

An Investigations‐Based Undergraduate Computational Chemistry Course

open access: yesJournal of Physical Organic Chemistry, Volume 39, Issue 11, November 2026.
Chemistry 164 is a hands‐on undergraduate computational chemistry course at Pomona College using publicly available materials (https://tinyurl.com/PomonaChem164) and structured around literature‐based investigations of organic structure and reactivity, isotope effects, NMR parameters, and organometallic systems.
Daniel J. O'Leary
wiley   +1 more source

Development of DNA Metalloenzymes Using a Rational Design Approach and Application in the Asymmetric Diels-Alder Reaction

open access: yes, 2015
Soyoung Park   +6 more
semanticscholar   +1 more source

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