Precision Chemistry for Protein Lysine Modification
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
Diels-Alder Click Chemistry as a Dynamic-Covalent Crosslinking Method in Spheroid-Encapsulating Hydrogels for Cartilage Engineering. [PDF]
van de Looij SM +8 more
europepmc +1 more source
Make‐Use‐Remake: Toward Indefinite Low‐Temperature Material Loops
We introduce a regenerable materials platform built from microparticles bound by a temperature‐responsive polymer shell, enabling strong, processable structures from diverse feedstocks. The material is shaped at low temperatures (80°C) using common manufacturing methods and reprocessed repeatedly in the presence of water, demonstrating stable ...
Nikola Křivánková +2 more
wiley +1 more source
A Multi‐Stimuli Transformational Network of Benzil‐Based Pd(II) Assemblies
Incorporation of a flexible and chemically reactive benzil backbone into the ligand structure allows it to access multiple conformations, enabling the formation of diverse homo‐ and heteroleptic Pd(II) assemblies with different nuclearities and topologies.
Zhiwei Zeng +5 more
wiley +2 more sources
Phytochemical Profiling of Mulberry Diels-Alder Adducts as Selective Butyrylcholinesterase Inhibitors: In Vitro Activity, Molecular Docking, and Molecular Dynamics Simulation. [PDF]
Cui X +8 more
europepmc +1 more source
Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco +5 more
wiley +1 more source
Sulfonyl-Directed Photoinduced Dehydro-Diels-Alder Reaction of Aryl Maleimides: Enabling Regioselective Naphthalene Synthesis. [PDF]
Song XH +5 more
europepmc +1 more source
Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics
This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley +1 more source
Regiochemical Control of Shape Morphing in Diels-Alder Covalent Adaptable Networks. [PDF]
Zhao Y, Moon J, Sukhishvili SA.
europepmc +1 more source
Chiral Morphing of Liquid Crystal Polymer Networks
This paper reviews how macroscopic chirality spontaneously arises from liquid crystal polymer materials. It describes how alignment is utilized to create the mechanical anisotropy, geometric misorientation and asymmetry that leads to chiral shape morphing, how shape selection between helicoids and helices arises, the techniques used to prepare these ...
Laurens T. de Haan
wiley +1 more source

