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Tolerability and Shared Decision-Making in the Hormonal Management of Endometriosis-Associated Pain. [PDF]

open access: yesBiomedicines
Pinto da Costa Viana D   +6 more
europepmc   +1 more source
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Dienogest

Drugs, 1998
The progestogen dienogest exhibits highly selective binding to the progesterone receptor. It has high progestational and significant antiandrogenic activity, but only moderate antigonadotrophic activity. Dienogest inhibits ovulation, produces secretory transformation of the endometrium and has antiproliferative effects.
R H, Foster, M I, Wilde
  +5 more sources

Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis: a before and after study

open access: yesFertility and Sterility, 2016
OBJECTIVE: To assess the proportion of patients satisfied with their treatment before and after a systematic change from norethindrone acetate to dienogest as the first-line progestin for symptomatic endometriosis.
Edgardo Somigliana   +2 more
exaly   +2 more sources

Effect of Dienogest therapy on the size of the endometrioma

open access: yesGynecological Endocrinology, 2020
Studies have been published on the efficacy of Dienogest in the management of pain symptoms in endometriosis. Nonetheless, few data are available on the reducing effect on endometrioma’s size.
Stefano Angioni   +2 more
exaly   +2 more sources

The pharmacology of dienogest

Maturitas, 2012
Dienogest (DNG) is a 19-nortestosterone derivative (a C-19 progestogen) with a cyanomethyl instead of an ethinyl group at the C-17 position, which may make the compound elicit fewer hepatic effects than other C-19 nortestosterone derivatives. Its similarity to norethisterone is reflected in its high endometrial efficacy, which could explain the high ...
Xiangyan, Ruan, H, Seeger, A O, Mueck
openaire   +3 more sources

Estradiol Valerate/Dienogest

Drugs, 2002
Estradiol valerate 2mg/dienogest 2mg is an oral estrogen/ progestogen formulation that has been approved throughout the European Union for the treatment of climacteric symptoms in postmenopausal women. Dienogest is a progestogen that combines the properties of both progesterone and 19-nortestosterone derivatives.
Keri, Wellington, Caroline M, Perry
openaire   +2 more sources

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