Results 151 to 160 of about 2,521 (195)
Some of the next articles are maybe not open access.
Drugs, 1998
The progestogen dienogest exhibits highly selective binding to the progesterone receptor. It has high progestational and significant antiandrogenic activity, but only moderate antigonadotrophic activity. Dienogest inhibits ovulation, produces secretory transformation of the endometrium and has antiproliferative effects.
R H, Foster, M I, Wilde
+5 more sources
The progestogen dienogest exhibits highly selective binding to the progesterone receptor. It has high progestational and significant antiandrogenic activity, but only moderate antigonadotrophic activity. Dienogest inhibits ovulation, produces secretory transformation of the endometrium and has antiproliferative effects.
R H, Foster, M I, Wilde
+5 more sources
Maturitas, 2012
Dienogest (DNG) is a 19-nortestosterone derivative (a C-19 progestogen) with a cyanomethyl instead of an ethinyl group at the C-17 position, which may make the compound elicit fewer hepatic effects than other C-19 nortestosterone derivatives. Its similarity to norethisterone is reflected in its high endometrial efficacy, which could explain the high ...
Xiangyan, Ruan, H, Seeger, A O, Mueck
openaire +3 more sources
Dienogest (DNG) is a 19-nortestosterone derivative (a C-19 progestogen) with a cyanomethyl instead of an ethinyl group at the C-17 position, which may make the compound elicit fewer hepatic effects than other C-19 nortestosterone derivatives. Its similarity to norethisterone is reflected in its high endometrial efficacy, which could explain the high ...
Xiangyan, Ruan, H, Seeger, A O, Mueck
openaire +3 more sources
Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment [PDF]
Archives of Gynecology and Obstetrics, 2011 Purpose To investigate the efficacy and safety of dienogest as a long-term treatment in endometriosis, with follow-up after treatment discontinuation. The study included women with endometriosis, who had previously completed a 12-week, placebo-controlled
Felice Petraglia +2 more
exaly +2 more sources
Drugs, 2002
Estradiol valerate 2mg/dienogest 2mg is an oral estrogen/ progestogen formulation that has been approved throughout the European Union for the treatment of climacteric symptoms in postmenopausal women. Dienogest is a progestogen that combines the properties of both progesterone and 19-nortestosterone derivatives.
Keri, Wellington, Caroline M, Perry
openaire +2 more sources
Estradiol valerate 2mg/dienogest 2mg is an oral estrogen/ progestogen formulation that has been approved throughout the European Union for the treatment of climacteric symptoms in postmenopausal women. Dienogest is a progestogen that combines the properties of both progesterone and 19-nortestosterone derivatives.
Keri, Wellington, Caroline M, Perry
openaire +2 more sources
Dienogest in the treatment of endometriosis
Expert Opinion on Pharmacotherapy, 2014Dienogest (DNG) is an oral progestin, derivative of 19-nortestosterone, that has recently been introduced for the treatment of endometriosis.This review examines the clinical efficacy, safety and tolerability of DNG in the treatment of endometriosis.
Bizzarri N +9 more
openaire +5 more sources
pharma-kritik, 2022
Mit Dienogest als Monopräparat steht eine vergleichsweise gut dokumentierte Behandlungsoption bei Endometriose zur Verfügung. Ob sich dieses Gestagen aber signifikant besser auf die Endometriose-bedingten Schmerzen auswirkt als andere Therapien (z.B. andere Gestagene), ist bisher nicht nachgewiesen.
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Mit Dienogest als Monopräparat steht eine vergleichsweise gut dokumentierte Behandlungsoption bei Endometriose zur Verfügung. Ob sich dieses Gestagen aber signifikant besser auf die Endometriose-bedingten Schmerzen auswirkt als andere Therapien (z.B. andere Gestagene), ist bisher nicht nachgewiesen.
openaire +1 more source
Dienogest - ein neues Progestagen
Archives of Gynecology and Obstetrics, 1993Dienogest stellt sich nach diesen Untersuchungen als ein Gestagen mit fehlender Androgenitat und weitgehender metabolischer Vertraglichkeit dar, das als eine Erweitwerung des verfugbaren Spektrums begrust werden kann.
G. Klinger, W. Carol, M. Oettel
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Drugs, 2009
Estradiol valerate/dienogest is an oral contraceptive for women that combines the natural estrogen estradiol with the 19-nortestosterone derivative dienogest in a four-phasic formulation. Estradiol valerate/dienogest demonstrated contraceptive efficacy in a large (n = 1377), noncomparative, multicentre study in women aged 18-50 years, with 13 ...
Sheridan M, Hoy, Lesley J, Scott
openaire +2 more sources
Estradiol valerate/dienogest is an oral contraceptive for women that combines the natural estrogen estradiol with the 19-nortestosterone derivative dienogest in a four-phasic formulation. Estradiol valerate/dienogest demonstrated contraceptive efficacy in a large (n = 1377), noncomparative, multicentre study in women aged 18-50 years, with 13 ...
Sheridan M, Hoy, Lesley J, Scott
openaire +2 more sources
Drugs, 2010
Dienogest (Visanne®) is a synthetic oral progestogen with unique pharmacological properties that is indicated at a dosage of 2 mg/day for the treatment of endometriosis. It is generally highly selective for the progesterone receptor and displays strong progestational effects and moderate antigonadotrophic effects, but no androgenic, glucocorticoid or ...
openaire +2 more sources
Dienogest (Visanne®) is a synthetic oral progestogen with unique pharmacological properties that is indicated at a dosage of 2 mg/day for the treatment of endometriosis. It is generally highly selective for the progesterone receptor and displays strong progestational effects and moderate antigonadotrophic effects, but no androgenic, glucocorticoid or ...
openaire +2 more sources