Results 11 to 20 of about 1,721 (143)
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach. [PDF]
Obstet Gynecol IntEndometriosis is a complex, estrogen‐dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, have significant side effects (weight gain, mood changes, decreased bone mineral density, and menopausal symptoms) and ...
Rai SK, Kumar R, Khan MI, Kumar A.
europepmc +2 more sources
Dienogest use and the risk of breast and gynecologic cancers: A nationwide population-based study. [PDF]
Int J Gynaecol ObstetAbstract Objective To evaluate whether dienogest exposure is associated with the risk of breast, endometrial, or tubo‐ovarian cancer in women with endometriosis. Methods In this nationwide retrospective cohort study (January 2012 to December 2023), we used the Korean National Health Insurance Review & Assessment Service database. Women aged 20–49 years
Jhang H +4 more
europepmc +2 more sources
Taiwanese Journal of Obstetrics & Gynecology, 2023 Objective: This comparative study aimed to evaluate the effect of postoperative dienogest treatment on serum anti-Mullerian hormone (AMH) levels in patients undergoing laparoscopic cystectomy of ovarian endometriomas. Materials and methods: A total of 71
Shih-Shien Weng +3 more
doaj +1 more source
Clinical experience of long-term use of dienogest after surgery for ovarian endometrioma [PDF]
Obstetrics & Gynecology Science, 2018 ObjectiveEndometriosis is a common and recurring gynecologic disease which have afflicting females of reproductive age. We investigated the efficacy of long-term, post-operative use of dienogest for ovarian endometrioma.MethodsWe studied 203 patients who
Anjali Chandra +8 more
doaj +1 more source
Novel Medicine for Endometriosis and Its Therapeutic Effect in a Mouse Model
Biomedicines, 2020 Current therapeutic medicines for endometriosis cannot be administered during assisted reproductive technology (ART) because they have bad effects during pregnancy.
Young Sang Kim +5 more
doaj +1 more source
Frontiers in Surgery, 2022 BackgroundEndometriosis is now considered to be a systemic disease rather than a disease that primarily affects the pelvis. Dienogest (DNG) has unique advantages in the treatment of endometriosis, but it also has side effects.
Yu’e Wu +4 more
doaj +1 more source
Preoperative Hemostatic Management for Refractory Abnormal Uterine Bleeding in Patients With von Willebrand Disease: A Case Report. [PDF]
Case Rep Obstet GynecolIntroduction von Willebrand disease (VWD) is the most frequent inherited bleeding disorder in women, characterized by quantitative or qualitative deficiency in von Willebrand factor (VWF). This deficiency in functional VWF has a dual effect on hemostasis, resulting in impaired coagulation; thus, it may cause unstoppable abnormal uterine bleeding (AUB).
Hiksas R +5 more
europepmc +2 more sources
Continuous Dienogest vs Cyclical Dienogest with Ethinyl Estradiol in the Management of Pelvic Endometriosis-A Prospective Interventional Study [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Endometriosis is a disease of adolescents and women of reproductive age group characterised by the presence of endometrial tissue outside the uterine cavity.
Pattianchi T Sangma +5 more
doaj +1 more source
Germany Endometriosis Pattern Changes; Prevalence and Therapy over 2010 and 2019 Years: A Retrospective Cross Sectional Study [PDF]
International Journal of Fertility and Sterility, 2022 Background: The aim of this study was to investigate whether the prevalence and the therapy patterns of endometriosis differ in 2010 and 2019. Materials and Methods: This retrospective cross-sectional study was based on the data from the IQVIA Disease ...
Jacob Goehring +3 more
doaj +1 more source
Reproductive Medicine and Biology, 2020 Purpose Surgery for endometriomas may cause detrimental effects on ovarian reserve. We evaluated the safety of three‐step laparoscopic surgery for endometriomas utilizing dienogest in terms of post‐surgical ovarian reserve.
Michio Kitajima +6 more
doaj +1 more source