Results 21 to 30 of about 2,521 (195)

Efficacy and safety of long-term administration of dienogest for deep infiltrative endometriosis [PDF]

РМЖ. Мать и дитя, 2019
V.G. Volkov1, N.E. Malykh2 1Tula State University, Tula, Russian Federation 2Tula Multidisciplinary Medical Center «Consultant Farm», Tula, Russian Federation Deep infiltrative endometriosis is a type of endometriosis characterized by 5-mm ...
Volkov V.G., N.E. Malykh
doaj   +1 more source

Effectiveness of the cyclic administration of dienogest in a case of pathological disappearance of intestinal endometriosis

International Journal of Women's Health, 2013
Ryo Tamura, Ikunosuke Tsuneki, Toru Yanase Department of Obstetrics and Gynecology, Niigata City General Hospital, Niigata, Japan Abstract: We have reported good control of atypical genital bleeding when using a cyclic administration of dienogest ...
Tamura R, Tsuneki I, Yanase T
doaj   +1 more source

Long-term therapy with dienogest or other oral cyclic estrogen-progestogen can reduce the need for ovarian endometrioma surgery [PDF]

Women's Health
Background: Almost 10% of women in reproductive age are diagnosed with ovarian endometriomas and can experience symptoms and infertility disorders. Ovarian endometriomas can be treated with medical or surgical therapy.
Federico Ferrari, Matteo Epis, Jvan Casarin, Giulia Bordi, Emanuele Baldo Gisone, Chiara Cattelan, Diego Oreste Rossetti, Giuseppe Ciravolo, Elisa Gozzini, Jacopo Conforti, Antonella Cromi, Antonio Simone Laganà, Fabio Ghezzi, Franco Odicino   +13 more
doaj   +4 more sources

The effect of dienogest and gonadotropin-releasing hormone agonist on pelvic pain after laparoscopic surgery for endometriosis: An RCT

International Journal of Reproductive BioMedicine
Background: Endometriosis is a chronic inflammatory condition associated with debilitating chronic pelvic pain that affects women’s quality of life.
Fatemeh Davari Tanha, Azam Rasti, Hamideh Pakniat, Shohreh Salimi Setudeh   +3 more
doaj   +2 more sources

Three-dimensional patient-derived endometriosis model for drug evaluation. [PDF]

Acta Obstet Gynecol Scand
In this study, we developed a coculturing model with stromal cells and epithelial organoids to mimic the endometriotic lesion and for further evaluation of drug effects. Abstract Introduction Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms.
Li Y, Shao W, Gao X, Wang Y, Li J, Zhang L, Xing Y, Su W, Cheng Y, Wang L, Liu S.   +10 more
europepmc   +2 more sources

Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach. [PDF]

Obstet Gynecol Int
Endometriosis is a complex, estrogen‐dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, have significant side effects (weight gain, mood changes, decreased bone mineral density, and menopausal symptoms) and ...
Rai SK, Kumar R, Khan MI, Kumar A.
europepmc   +2 more sources

Dienogest use and the risk of breast and gynecologic cancers: A nationwide population-based study. [PDF]

Int J Gynaecol Obstet
Abstract Objective To evaluate whether dienogest exposure is associated with the risk of breast, endometrial, or tubo‐ovarian cancer in women with endometriosis. Methods In this nationwide retrospective cohort study (January 2012 to December 2023), we used the Korean National Health Insurance Review & Assessment Service database. Women aged 20–49 years
Jhang H, Kim S, Park HT, Shin JY, Choe SA.   +4 more
europepmc   +2 more sources

Treatment of endometriosis with dienogest in combination with traditional Chinese medicine: A systematic review and meta-analysis

Frontiers in Surgery, 2022
BackgroundEndometriosis is now considered to be a systemic disease rather than a disease that primarily affects the pelvis. Dienogest (DNG) has unique advantages in the treatment of endometriosis, but it also has side effects.
Yu’e Wu, Yujie Liu, Huanhuan Jia, Chao Luo, Huan Chen   +4 more
doaj   +1 more source

Dienogest and the breast

Gynecological Endocrinology, 2009
In a clinical pilot study, 21 women with endometriosis have been primarely treated with dienogest 2 x 10 mg daily p.o. for 24 weeks. Besides the effect on endometriosis the action of such high-dose progestogen treatment on the breast was evaluated by breast ultrasound prior to medication and at 24 weeks of medical treatment. In all women, a significant
Adolf E, Schindler, Alexandria, Henkel, Bernd, Christensen, Michel, Oettel, Claudia, Moore   +4 more
openaire   +2 more sources

Continuous Dienogest vs Cyclical Dienogest with Ethinyl Estradiol in the Management of Pelvic Endometriosis-A Prospective Interventional Study [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Endometriosis is a disease of adolescents and women of reproductive age group characterised by the presence of endometrial tissue outside the uterine cavity.
Pattianchi T Sangma, Palash Mazumder, Dipa Mullick, Shyamali Dutta, Sukumar Mitra, Sohini Sen   +5 more
doaj   +1 more source