Results 11 to 20 of about 4,216 (212)
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach. [PDF]
Obstet Gynecol IntEndometriosis is a complex, estrogen‐dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, have significant side effects (weight gain, mood changes, decreased bone mineral density, and menopausal symptoms) and ...
Rai SK, Kumar R, Khan MI, Kumar A.
europepmc +2 more sources
Dienogest use and the risk of breast and gynecologic cancers: A nationwide population-based study. [PDF]
Int J Gynaecol ObstetAbstract Objective To evaluate whether dienogest exposure is associated with the risk of breast, endometrial, or tubo‐ovarian cancer in women with endometriosis. Methods In this nationwide retrospective cohort study (January 2012 to December 2023), we used the Korean National Health Insurance Review & Assessment Service database. Women aged 20–49 years
Jhang H +4 more
europepmc +2 more sources
Indonesian Journal of Obstetrics and Gynecology, 2020 Objective: Comparing therapeutic effectiveness, safety profile, and adherence between Dienogest and postoperative Leuprolide Acetate in women with endometriosis who underwent laparoscopy.
Joko P. Purwanto +3 more
doaj +1 more source
Gynecology Obstetrics & Reproductive Medicine, 2020 Objective: Endometriosis is a common gynecological condition that affects many women of reproductive age worldwide and is a major cause of pain and infertility.
Tolga Karacan +4 more
doaj +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2023 Objective: This comparative study aimed to evaluate the effect of postoperative dienogest treatment on serum anti-Mullerian hormone (AMH) levels in patients undergoing laparoscopic cystectomy of ovarian endometriomas. Materials and methods: A total of 71
Shih-Shien Weng +3 more
doaj +1 more source
Novel Medicine for Endometriosis and Its Therapeutic Effect in a Mouse Model
Biomedicines, 2020 Current therapeutic medicines for endometriosis cannot be administered during assisted reproductive technology (ART) because they have bad effects during pregnancy.
Young Sang Kim +5 more
doaj +1 more source
Clinical experience of long-term use of dienogest after surgery for ovarian endometrioma [PDF]
Obstetrics & Gynecology Science, 2018 ObjectiveEndometriosis is a common and recurring gynecologic disease which have afflicting females of reproductive age. We investigated the efficacy of long-term, post-operative use of dienogest for ovarian endometrioma.MethodsWe studied 203 patients who
Anjali Chandra +8 more
doaj +1 more source
Frontiers in Surgery, 2022 BackgroundEndometriosis is now considered to be a systemic disease rather than a disease that primarily affects the pelvis. Dienogest (DNG) has unique advantages in the treatment of endometriosis, but it also has side effects.
Yu’e Wu +4 more
doaj +1 more source
Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]
, 2009 Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Friese, Klaus +6 more
core +1 more source
Gynecological Endocrinology, 2009 In a clinical pilot study, 21 women with endometriosis have been primarely treated with dienogest 2 x 10 mg daily p.o. for 24 weeks. Besides the effect on endometriosis the action of such high-dose progestogen treatment on the breast was evaluated by breast ultrasound prior to medication and at 24 weeks of medical treatment. In all women, a significant
Adolf E, Schindler +4 more
openaire +2 more sources