Results 21 to 30 of about 404,333 (267)

The effects of diet and streptozotocin on metabolism and gut microbiota in a type 2 diabetes mellitus mouse model

open access: yesFood and Agricultural Immunology, 2020
Diabetes mellitus is a metabolic disorder disease. Diabetes models can be established using diet and/or chemical agents. However, the effects of these methods on the intestinal microbiota are poorly understood. In this study, C57BL/6 mice were fed with a
Ruiyang Yin   +4 more
doaj   +1 more source

High-Fructose/High-Fat Diet Downregulates the Hepatic Mitochondrial Oxidative Phosphorylation Pathway in Mice Compared with High-Fat Diet Alone

open access: yesCells, 2022
Both high-fat diet (HFD) alone and high-fructose plus HFD (HFr/HFD) cause diet-induced non-alcoholic fatty liver disease in murine models. However, the mechanisms underlying their impacts on inducing different levels of liver injury are yet to be ...
Milton D. Chiang Morales   +6 more
doaj   +1 more source

Beneficial effects of an alternating high- fat dietary regimen on systemic insulin resistance, hepatic and renal inflammation and renal function.

open access: yesPLoS ONE, 2012
BackgroundAn Alternating high- cholesterol dietary regimen has proven to be beneficial when compared to daily high- cholesterol feeding. In the current study we explored whether the same strategy is applicable to a high- fat dietary regimen.ObjectiveTo ...
Gopala K Yakala   +7 more
doaj   +1 more source

Dietary-induced hypertrophic–hyperplastic obesity in mice

open access: yesJournal of Lipid Research, 1974
Metabolically intact NMRI mice and genetically obese NZO mice were fed ad lib. either a high-carbohydrate diet (standard) or a high-fat diet for a period of about 11 (NMRI mice) or 38 (NZO mice) wk.
L. Herberg   +3 more
doaj   +1 more source

Effects of Excess Energy Intake on Glucose and Lipid Metabolism in C57BL/6 Mice. [PDF]

open access: yesPLoS ONE, 2016
Excess energy intake correlates with the development of metabolic disorders. However, different energy-dense foods have different effects on metabolism.
Jing Pang   +5 more
doaj   +1 more source

Effects of Maternal Resveratrol on Maternal High-Fat Diet/Obesity with or without Postnatal High-Fat Diet [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
To examine the effects of maternal resveratrol in rats borne to dams with gestational high-fat diet (HFD)/obesity with or without postnatal high-fat diet. We first tested the effects of maternal resveratrol intake on placenta and male fetus brain in rats borne to dams with gestational HFD/obesity.
Mei-Hsin Hsu   +6 more
openaire   +2 more sources

P2Y2 Receptor Promotes High-Fat Diet-Induced Obesity [PDF]

open access: yesFrontiers in Endocrinology, 2020
P2Y2, a G protein-coupled receptor (R), is expressed in all organs involved in the development of obesity and insulin resistance. To explore the role of it in diet-induced obesity, we fed male P2Y2-R whole body knockout (KO) and wild type (WT) mice (B6D2 genetic background) with regular diet (CNT; 10% calories as fat) or high-fat diet (HFD; 60 ...
Yue Zhang   +12 more
openaire   +3 more sources

High‐Fat‐Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe high‐fat Western diet is postulated to be associated with the onset and progression of Alzheimer's disease (AD). However, the role of high‐fat‐diet consumption in AD pathology is unknown.
Bowen Lin   +5 more
doaj   +1 more source

Methylmercury-Induced Metabolic Alterations in Caenorhabditis elegans Are Diet-Dependent

open access: yesToxics, 2021
Methylmercury (MeHg) is a well-known neurotoxicant; however, its role in metabolic diseases has been gaining wider attention. Chronic exposure to MeHg in human populations shows an association with diabetes mellitus and metabolic syndrome (MS).
Nicole Crawford   +9 more
doaj   +1 more source

Comparison of Three Different Diet-Induced Non Alcoholic Fatty Liver Disease Protocols in Rats: A Pilot Study

open access: yesPharmaceutical Sciences, 2016
Background: There are many methods for inducing non-alcoholic fatty liver disease (NAFLD) in experimental animals. Due to the diversity of these methods and different variables involved in choosing the appropriate one, this study aimed to examine the ...
Sara Shojaei Zarghani   +3 more
doaj   +1 more source

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