Results 11 to 20 of about 15,949,045 (258)

High-Fat Diet : Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse [PDF]

open access: yes, 2010
Background: Obesity induced by high fat (HF) diet is associated with inflammation which contributes to development of insulin resistance. Most prior studies have focused on adipose tissue as the source of obesity-associated inflammation.
Ding, Shengli   +7 more
core   +6 more sources

Isoenergetic feeding of low carbohydrate-high fat diets does not increase brown adipose tissue thermogenic capacity in rats [PDF]

open access: yes, 2012
Low-carbohydrate, high-fat (LC-HF) diets are popular for inducing weight loss in overweighed adults. Adaptive thermogenesis increased by specific effects of macronutrients on energy expenditure has been postulated to induce this weight loss.
Bidlingmaier, Martin   +54 more
core   +2 more sources

Long term high-fat diet, wheel running, and blood glucose in rats [PDF]

open access: yes, 2003
Rats feeding high-fat diet tend to get more weight than rats feeding usual meal. In order to examine high-fat diet induce insufficient glucose metabolism, and to examine physical exercise affects the metabolism, 9 week-old rats fed high-fat diet (41% fat)
Aoki, Takako   +5 more
core   +1 more source

High-Fructose/High-Fat Diet Downregulates the Hepatic Mitochondrial Oxidative Phosphorylation Pathway in Mice Compared with High-Fat Diet Alone

open access: yesCells, 2022
Both high-fat diet (HFD) alone and high-fructose plus HFD (HFr/HFD) cause diet-induced non-alcoholic fatty liver disease in murine models. However, the mechanisms underlying their impacts on inducing different levels of liver injury are yet to be ...
Milton D. Chiang Morales   +6 more
doaj   +1 more source

Effects of Orlistat and herbal mixture extract on brain, testes functions and oxidative stress biomarkers in a rat model of high fat diet

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2014
This study was designed to assess the effectiveness of herbal mixture extracts of pumpkin seed oil, peanuts shell and Orlistat on brain, testes functions, oxidative stress biomarkers and histopathological changes in male albino rats administered high fat
Sanaa R. Galaly   +3 more
doaj   +1 more source

The effects of diet and streptozotocin on metabolism and gut microbiota in a type 2 diabetes mellitus mouse model

open access: yesFood and Agricultural Immunology, 2020
Diabetes mellitus is a metabolic disorder disease. Diabetes models can be established using diet and/or chemical agents. However, the effects of these methods on the intestinal microbiota are poorly understood. In this study, C57BL/6 mice were fed with a
Ruiyang Yin   +4 more
doaj   +1 more source

High-Fat Diet Increases Bone Loss by Inducing Ferroptosis in Osteoblasts

open access: yesStem Cells International, 2022
Current research suggests that chronic high-fat dietary intake can lead to bone loss in adults; however, the mechanism by which high-fat diets affect the development of osteoporosis in individuals is unclear.
RunJiu Zhu   +8 more
doaj   +1 more source

Methylmercury-Induced Metabolic Alterations in Caenorhabditis elegans Are Diet-Dependent

open access: yesToxics, 2021
Methylmercury (MeHg) is a well-known neurotoxicant; however, its role in metabolic diseases has been gaining wider attention. Chronic exposure to MeHg in human populations shows an association with diabetes mellitus and metabolic syndrome (MS).
Nicole Crawford   +9 more
doaj   +1 more source

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota [PDF]

open access: yes, 2011
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside
Klopp, Christophe   +45 more
core   +1 more source

Orlistat exerts anti-obesity and anti-tumorigenic effects in a transgenic mouse model of endometrial cancer

open access: yesFrontiers in Oncology, 2023
IntroductionAmong all cancers, endometrial cancer is most strongly associated with obesity, with more than 65% of endometrial cancers attributable to obesity and being overweight.
Guangxu Xu   +17 more
doaj   +1 more source

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