Results 41 to 50 of about 431,652 (264)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Network meta-analysis of the effects of different dietary patterns on patients with metabolic syndrome

Frontiers in Nutrition
BackgroundDietary patterns play an important role in the management of metabolic syndrome (MetS). Previous meta-analyses have shown that the ketogenic diet, the Dietary Approaches to Stop Hypertension (DASH) diet, the vegetarian diet, the Mediterranean ...
Jie Lv, Jie Lv, Shiyu Jiao, Shiyu Jiao, Wenjing Li, Shuo Ding, Li Ma, Qian Zhang, Qian Zhang   +8 more
doaj   +1 more source

Influence of Dietary Inulin on Fecal Microbiota, Cardiometabolic Risk Factors, Eicosanoids, and Oxidative Stress in Rats Fed a High-Fat Diet

Foods, 2022
The present study examined the influence of inulin on fecal microbiota, cardiometabolic risk factors, eicosanoids, and oxidative stress in rats on a high-fat (HF) diet.
Bernat Miralles-Pérez, Maria Rosa Nogués, Vanessa Sánchez-Martos, Àngels Fortuño-Mar, Sara Ramos-Romero, Josep L. Torres, Julia Ponomarenko, Susana Amézqueta, Xiang Zhang, Marta Romeu   +9 more
doaj   +1 more source

Reducing Cardiovascular Disease Risk with Diet [PDF]

Obesity Research, 2001
AbstractObjective: Past research efforts to determine the influence of the diet on cardiovascular (CV) health have focused on the individual roles of specific dietary components with debatable success. Awareness of the impact and complexity of nutrient interactions has expanded in recent years to include assessment of dietary patterns as they ...
D A, McCarron, M E, Reusser
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sex Modulates Lactobacillus johnsonii N6.2 and Phytophenol Effectiveness in Reducing High Fat Diet Induced mTOR Activation in Sprague-Dawley Rats

Frontiers in Microbiology, 2018
Metabolic syndrome (MetS) is the underlying cause of some devastating diseases, including type 2 diabetes and cardiovascular disease. These diseases have been associated with over-activation of the mechanistic Target of Rapamycin (mTOR) pathway.
Danielle N. Kling, Evon M. DeBose-Scarlett, Leandro D. Teixeira, Salvador A. Gezan, Graciela L. Lorca, Claudio F. Gonzalez   +5 more
doaj   +1 more source

Effect of Diet Composition on Excreta Composition and Ammonia Emissions from Growing-Finishing Pigs

Animals, 2022
This study aimed to investigate the impact of decreased crude protein (CP) levels (by 2% units) or acidifying diets (by adding 10 g benzoic acid/kg diet in combination with replacing a part of CaCO3 by about 10 g Ca-formate/kg diet) on urine, feces and ...
Phung Le Dinh, Carola M. C. van der Peet-Schwering, Nico W. M. Ogink, André J. A. Aarnink   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Are Adult Cats Fed on Wet Maintenance Diets Less at Risk of Developing Chronic Kidney Disease Compared to Adult Cats Fed on Dry Maintenance Diets?

Veterinary Evidence, 2017
A comprehensive search of the available veterinary literature found three studies which assess whether feeding wet or dry maintenance diets place cats at an increased risk of chronic kidney disease (CKD) diagnosis.
Catherine Anne McLeonard
doaj   +1 more source