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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Effects of Short-term Dietary Intervention for Obese Patients with Abnormal Glucose Metabolism [PDF]
Background Recent studies show that dietary interventions can induce remission of type 2 diabetes mellitus (T2DM) in individuals with overweight or obesity, but related evidence from China remains limited. Objective To evaluate the clinical efficacy of a
SHENG Luguang, LIU Dandan, LIU Weibin, LU Jun, LEI Tao, CHEN Qingguang, LU Hao, XU Bilin
doaj +1 more source
Introduction and purpose. Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder diagnosed in women. Symptoms include menstrual disorders, infertility, acne, seborrhea, hirsutism and carbohydrate metabolism disorders.
Wiktoria Kotusiewicz +7 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Environmental Life Cycle Assessment of Diets with Improved Omega-3 Fatty Acid Profiles. [PDF]
A high incidence of cardiovascular disease is observed worldwide, and dietary habits are one of the risk factors for these diseases. Omega-3 polyunsaturated fatty acids in the diet help to prevent cardiovascular disease.
Carla R V Coelho +2 more
doaj +1 more source
Preventing childhood obesity by reducing consumption of carbonated drinks: cluster randomised controlled trial [PDF]
Objective To determine if a school based educational programme aimed at reducing consumption of carbonated drinks can prevent excessive weight gain in children. Design Cluster randomised controlled trial.
David Kerr +7 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Influence of Reduced Nitrogen Diets on Ammonia Emissions from Cattle Feedlot Pens
Reducing crude protein (CP) in livestock diets may lower ammonia emissions. A feeding trial was conducted with crossbred steers at the Southeast Colorado Research Center in Lamar, Colorado from December 2009 to March 2010.
Elin Westover +6 more
doaj +1 more source
: This study was conducted to evaluate the effect of licorice and rutin on production performance, egg quality, and mucosa antioxidant levels in Chinese yellow quail.
Yan Li +8 more
doaj +1 more source

