Results 61 to 70 of about 317,139 (307)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Seasonal Diet Selection and Nutritional Niche of Mule Deer in a Chihuahuan Semi-Desert
Ruminant herbivores interact dynamically with their food resources, especially in deserts, where plant availability fluctuates sharply across seasons. We evaluated how seasonal food availability and the nutritional traits of preferred plants shape the ...
John F. Aristizabal +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Selection of forage and habitats is driven by nutritional needs of individuals. Some species may sacrifice nutritional quality of forage for the mother in favor of safety of offspring (risk-averse strategy), immediately following parturition.
Marcus E. Blum +7 more
doaj +1 more source
Exploring the breeding diet of the Black Sparrowhawk (Accipiter Melanoleucus) on the Cape Peninsula [PDF]
This study investigates the diet of breeding Black Sparrowhawks (Accipiter melanoleucus) on the Cape Peninsula of South Africa. Macro-remains of prey were collected from below and around the vicinity of nests throughout the breeding seasons of 2012 and ...
Baigrie, Bruce
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Selective exposure shapes the Facebook news diet
PLOS One Published: March 13 ...
Cinelli, Matteo +5 more
openaire +6 more sources
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Background Mixtures with birdsfoot trefoil (BFT) increase herbage intake in grazing cattle. We hypothesized that BFT spatially separated from grasses would increase preferential grazing of BFT and herbage intake compared to grass and BFT in mixed rows ...
Michael D. Peel +8 more
doaj +1 more source

