Results 61 to 70 of about 317,139 (307)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Seasonal Diet Selection and Nutritional Niche of Mule Deer in a Chihuahuan Semi-Desert

open access: yesWild
Ruminant herbivores interact dynamically with their food resources, especially in deserts, where plant availability fluctuates sharply across seasons. We evaluated how seasonal food availability and the nutritional traits of preferred plants shape the ...
John F. Aristizabal   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Variation in diet of desert bighorn sheep (Ovis canadensis nelsoni): Tradeoffs associated with parturition

open access: yesFrontiers in Ecology and Evolution, 2023
Selection of forage and habitats is driven by nutritional needs of individuals. Some species may sacrifice nutritional quality of forage for the mother in favor of safety of offspring (risk-averse strategy), immediately following parturition.
Marcus E. Blum   +7 more
doaj   +1 more source

Exploring the breeding diet of the Black Sparrowhawk (Accipiter Melanoleucus) on the Cape Peninsula [PDF]

open access: yes, 2013
This study investigates the diet of breeding Black Sparrowhawks (Accipiter melanoleucus) on the Cape Peninsula of South Africa. Macro-remains of prey were collected from below and around the vicinity of nests throughout the breeding seasons of 2012 and ...
Baigrie, Bruce
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Selective exposure shapes the Facebook news diet

open access: yesPLOS ONE, 2020
PLOS One Published: March 13 ...
Cinelli, Matteo   +5 more
openaire   +6 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Intake and diet preference of dairy heifers grazing mixed or alternating rows of birdsfoot trefoil and cool‐season grasses

open access: yesGrassland Research
Background Mixtures with birdsfoot trefoil (BFT) increase herbage intake in grazing cattle. We hypothesized that BFT spatially separated from grasses would increase preferential grazing of BFT and herbage intake compared to grass and BFT in mixed rows ...
Michael D. Peel   +8 more
doaj   +1 more source

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