Results 151 to 160 of about 332,290 (332)
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia+12 more
wiley +1 more source
Effects of changes in dietary calcium on neuromuscular transmission
G. L. Brown, A. McGehee Harvey
openalex +2 more sources
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao+14 more
wiley +1 more source
Nutritional management of equine sabulous urolithiasis : a case report [PDF]
C
Dupont, Sofie+2 more
core +1 more source
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee+5 more
wiley +1 more source
Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo+10 more
wiley +1 more source
Association between dietary calcium, potassium, and magnesium consumption and glaucoma. [PDF]
Zhang Y+5 more
europepmc +1 more source
Aortic dissection (AD) is accompanied by a decrease in CCDC80 in vascular smooth muscle cells (VSMCs). CCDC80 can interact with JAK2, and VSMC‐specific CCDC80 deficiency accelerates the progression of AD by activating the JAK2/STAT3 pathway involved in regulating the phenotype switching and function of VSMCs.
Qingqing Xiao+18 more
wiley +1 more source
There should be a dietary guideline for calcium [PDF]
openaire +2 more sources