Results 81 to 90 of about 8,470,846 (303)

Correlation between dietary factors and Parkinson’s disease revealed by the analysis of Mendelian randomization

Frontiers in Nutrition
BackgroundThe intricate interplay between dietary habits and the development of Parkinson’s Disease (PD) has long been a subject of scientific inquiry. Mendelian Randomization (MR) emerges as a potent tool, harnessing genetic variants to infer causality ...
Shan Zeng, Aishanjiang Yusufujiang, Chunli Zhang, Chen Yang, Hongyan Li   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Dietary fat intake and obesity : an empirical study in Greek adults. [PDF]

The empirical evidence concerning the associations between diet, particularly fat intake, and obesity is inconclusive. The aim of the present study was to investigate cross-sectional associations between general and central ...
Lagiou, Areti
core   +1 more source

Dietary Factors and the Development of Asthma [PDF]

Immunology and Allergy Clinics of North America, 2008
Asthma and allergies continue to be major public health problems in affluent westernized countries. Changes in dietary habits dating from before the increase in asthma prevalence may have a role in the development of asthma and allergies. Many studies have investigated the role of specific nutrients in asthma and allergies, and intervention studies ...
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dietary Energy Density in Relation to Subsequent Changes of Weight and Waist Circumference in European Men and Women [PDF]

, 2009
Background - Experimental studies show that a reduction in dietary energy density (ED) is associated with reduced energy intake and body weight.
Nita G Forouhi, Marianne Uhre Jakobsen, Saris, W.H., Masala, G, Du, H., Wareham, N.J., Jebb, Susan A, Wareham, Nicholas J, Vanessa Ginder, Sorensen, T., Jakobsen Marianne Uhre, Sørensen, TI, Tjønneland Anne, Nicholas J Wareham, Palli, D, van der Aa, A., Sørensen Thorkild I. A., Du, Huaidong, Wareham, N., Buijsse, Brian, Tjønneland, A, Jebb, S.A., Halkjaer, J, Masala Giovanna, Kim Overvad, Palli, Domenico, Feskens, Edith J M, Ginder, V., Palli Domenico, Jakobsen, MU, Halkjaer, Jytte, Masala, G., Saris, WH, Wim H M Saris, Annika Steffen, Ginder, Vanessa, Forouhi Nita G., Overvad, K., Steffen, A., Feskens, E.J.M., Forouchi, N.G., Forouhi, NG, Thorkild I A Sørensen, Wareham Nicholas J., Saris, Wim H M, Forouhi, Nita G, Steffen, Annika, Halkjær Jytte, Saris Wim H. M., Jebb, SA, Masala, Giovanna, Tjonneland, A., Du Huaidong, Edith J M Feskens, van der A, Daphne L, Giovanna Masala, Steffen Annika, Feskens, E.J., Domenico Palli, Huaidong Du, Buijsse, B, Ginder Vanessa, Jebb Susan A., Overvad Kim, Feskens Edith J. M., Forouhi, N.G., Jakobsen, Marianne Uhre, Daphne L van der A, Overvad, Kim, Sørensen, Thorkild I A, Overvad, K, Jakobsen, M.U., Van Der A, DL, Jytte Halkjaer, Tjønneland, Anne, Palli, D., Buijsse Brian, Sorensen, T.I., Ginder, V, van der A Daphne L., Buijsse, B., Steffen, A, Halkjaer, J., Du, H, Wareham, NJ, Anne Tjønneland, Brian Buijsse, Feskens, EJ, Susan A Jebb   +88 more
core   +2 more sources

Global, regional and national burden of ischemic heart disease attributable to suboptimal diet, 1990–2023: a Global Burden of Disease study

Ischemic heart disease (IHD) remains a leading cause of death worldwide, with dietary risks being its most significant modifiable factor. Here, using the Global Burden of Diseases, Injuries and Risk Factors Study 2023, we estimated the mortality and ...
Lee, Sooji, Adebayo, Oladimeji Muritala, Addo, Isaac Yeboah, Abate, Yohannes Habtegiorgis, Agide, Feleke Doyore, Abtahi, Dariush, Abukhadijah, Hana J., Abbaspour, Elahe, Afrooghe, Arya, Agyemang-Duah, Williams, Ahmad, Aqeel, Lee, Hayeon, Abbas, Nasir, Adiga, Usha, Abdullahi, Auwal, Abbastabar, Hedayat, ElHafeez, Samar Abd, Abiodun, Olumide, Abu-Gharbieh, Eman, Aburuz, Salahdein, Abdulkader, Rizwan Suliankatchi, Afolabi, Aanuoluwapo Adeyimika, Son, Yejun, Sakilah Adnani, Qorinah Estiningtyas, Fischer, Florian, Abohashem, Shady, Abubakar, Aminu Kende, Abdollahi, Mohammad, Abu-Zaid, Ahmed, Aalruz, Hasan, Adhikari, Kishor, Abbafati, Cristiana, Abreu, Lucas Guimarães, Abiodun, Olugbenga Olusola, Aboagye, Richard Gyan, Shin, Jae Il, Abdisa, Wakgari Mosisa, Abdi, Parsa, Abdoun, Meriem, Adane, Mesafint Molla, Ahinkorah, Bright Opoku, Abubakar, Bilyaminu, Adetunji, Charles Oluwaseun, Adedokun, Kamoru Ademola, Adedoyin, Rufus Adesoji, Afzal, Saira, Adeyeoluwa, Temitayo Esther, Agarwal, Prerna, Adetunji, Juliana Bunmi, Afzal, Muhammad Sohail   +49 more
core   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

The effects of dietary intervention on HIV dyslipidaemia : a systematic review and meta-analysis [PDF]

, 2012
Background Efficacy of dietary intervention for treatment and prevention of HIV-related lipid disturbances has not been well established. Methods We conducted a systematic search of electronic databases supplemented with manual searches and ...
Thomas, G. Neil, Yen-Fu Chen, Shahrad Taheri (57360), G. Neil Thomas (159433), Connock, Martin, Taheri, S., Connock Martin, Russell, Tracy, Tracy Russell, Thomas, G Neil, Shahrad Taheri, Clare Stradling, Clare Stradling (159408), Chen Yen-Fu, Connock, M., Thomas G. Neil, Chen, Yen-Fu, Chen, Y-F.‏‎, Martin Connock (159426), G Neil Thomas, Tracy Russell (159420), Russell Tracy, Yen-Fu Chen (159414), Chen, Yen-Fu; id_orcid, Martin Connock, Taheri, Shahrad, Stradling Clare, Taheri Shahrad, Stradling, Clare   +28 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source