Results 101 to 110 of about 16,442 (242)

Beyond medication: Unveiling the role of diet and lifestyle in fatty liver disease management

Human Nutrition & Metabolism
Background: Fatty liver disease (FLD), also known as hepatic steatosis, is characterized by the accumulation of fat in the liver, which can lead to inflammation, scarring, and severe liver damage.
Iahtisham-Ul-Haq, Muhammad Nadeem, Aanchal Sharma, Robert Mugabi, Muhammad Waseem, Gulzar Ahmad Nayik   +5 more
doaj   +1 more source

Fats, Fire and Bronze Age Funerary Rites: Organic Residue Analysis of Wide Horizontal Rim Vessels From Burial Contexts in Northwest Portugal

Archaeometry, EarlyView.
ABSTRACT This study presents the first GC‐MS–based analyses of wide horizontal rim vessels with well‐defined funerary contexts, from Middle Bronze Age Portugal (Quinta do Amorim 2 and Pego). Organic residues from two vessels revealed ruminant fats and plant oils, alongside molecular markers of heat exposure.
João Vinícius Back, César Oliveira, Ana M. S. Bettencourt, Hugo Aluai Sampaio, Luciano Vilas Boas, Luís Gonçalves   +5 more
wiley   +1 more source

An Archaeometric Approach to Reveal Organic Compounds via GC‐MS Analyses of Two Discovered Incense Burners at Daba Al‐Bayah

Archaeometry, EarlyView.
ABSTRACT This study focuses on two terracotta incense burners discovered in the Daba Al‐Bayah necropolis in the Musandam Peninsula (Oman), associated with an Iron Age collective tomb (LCG‐2). Through gas chromatography–mass spectrometry (GC‐MS), the organic residues preserved within these artifacts were analyzed to investigate their use and ...
Francesco Genchi, Federica Spagnoli, Vittorio Vinciguerra, Stefania Garzoli   +3 more
wiley   +1 more source

Sustainable dyeing of silk with curled dock (Rumex crispus) extract for trace element removal, ultraviolet protection, antimicrobial and anti‐oxidant activity

Coloration Technology, EarlyView.
Abstract This study investigated the dyeability and functionality of silk dyed with curled dock leaf extract. The effects of sugar content and turbidity in the extracted dye solution on dyeing were analysed, along with K/S values and colour fastness, under varying temperatures and times.
Youngmi Park
wiley   +1 more source

Metabolic liver disease: A summary of major guidelines and identifying opportunities to improve future guidelines

Diabetes, Obesity and Metabolism, EarlyView.
Abstract The clinical management of metabolic dysfunction‐associated steatotic liver disease (MASLD) and metabolic dysfunction‐associated steatohepatitis (MASH) is undergoing rapid evolution, driven by advances in noninvasive diagnostics and the recent approval of liver‐directed therapies.
Fernando Bril
wiley   +1 more source

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

The FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova, Caroline M. Ferreira, Katrina P. Montales, Francisco Villalobos, Alexandra J. Brownstein, Rebeca Acín‐Pérez, Gabrielly S. Ferreira, Anthony E. Jones, Linsey Stiles, Ajit S. Divakaruni, Marc Liesa, Orian S. Shirihai, Marcus F. Oliveira   +12 more
wiley   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

Individualized Diets in Patients with Kidney Disease and Kidney Transplants: A Narrative Review

Life
Chronic kidney disease (CKD) is a widespread condition with significant cardiovascular risks and a progression to end-stage kidney failure. In recent years, increasing attention has been paid to the role of dietary interventions as a factor capable of ...
Lilio Hu, Greta Borelli, Elisa Gessaroli, Chiara Ruotolo, Sofia Bin, Giuliana Papalia, Gemma Patella, Maria Elena Liberti, Olga Baraldi, Gianluigi Zaza, Irene Capelli, Michele Provenzano   +11 more
doaj   +1 more source

Larval Arctic cod (Boreogadus saida) exhibit stronger developmental and physiological responses to temperature than to elevated pCO2

Journal of Fish Biology, EarlyView.
Abstract High‐latitude ecosystems are simultaneously warming and acidifying under ongoing climate change. Arctic cod (Boreogadus saida) are a key species in the Arctic Ocean and have demonstrated sensitivity to ocean warming and acidification as adults and embryos, but their larval sensitivity to the combined stressors is unknown. In a laboratory multi‐
Emily Slesinger, Louise A. Copeman, Benjamin J. Laurel, Mary Beth R. Hicks, Paul J. Iseri, Michelle A. Stowell, Thomas P. Hurst   +6 more
wiley   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

Plant, Cell &Environment, EarlyView.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador, Ailin Liu, Ming‐Sin Ng, Yee‐Shan Ku, Siu H. J. Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source