Results 121 to 130 of about 173,728 (337)

Oils and fats on food: is it possible to have a healthy diet? [PDF]

open access: yes, 2017
Oils and fats are an important part of our diet as components of many food formulations. Thus, they are retailed for domestic or hostelry uses and broadly used by food industry for the elaboration of margarines, ice cream, canned food, pre-cooked ...
Garcés Mancheño, Rafael   +3 more
core  

Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRα signaling

open access: yesCell Reports
Summary: Dietary fat composition has changed substantially during the obesity epidemic. As adipocyte hyperplasia is a major mechanism of adipose expansion, we aim to ascertain how dietary fats affect adipogenesis during obesity.
Allison Wing   +15 more
doaj   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

open access: yesAdvanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li   +9 more
wiley   +1 more source

Development of a food antioxidant complex of plant origin [PDF]

open access: yes, 2019
Розроблено антиоксидантний комплекс для використання в оліях, жирах та продуктах харчування, що потребують збагачення біологічно активними речовинами рослинного походження. Досліджено раціональні умови одержан- ня водно-етанольних екстрактів із рослинної
Bilous, O.   +9 more
core  

Oral Celastrol Micelles Forming High‐Density Lipoprotein Corona Targeting Hepatocytes for MASLD Treatment

open access: yesAdvanced Science, EarlyView.
Upon oral administration, OPDEA‐PCL/CEL micelles passed through the stomach acid intact, then quickly penetrated the intestinal mucus and transported into circulation, where they captured HDL to form a protein corona and target hepatocyte SR‐B1 receptors, inducing endocytosis.
Chang Xu   +11 more
wiley   +1 more source

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

open access: yesAdvanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li   +24 more
wiley   +1 more source

Dietary Fats and Cognitive Status in Italian Middle-Old Adults. [PDF]

open access: yesNutrients, 2023
Currenti W   +8 more
europepmc   +1 more source

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