Results 61 to 70 of about 2,290,705 (387)

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.

Journal of the American Society of Nephrology, 2020
BACKGROUND Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes.
Y. Li, Xiaochen Chen, Tony K Kwan, Y. Loh, J. Singer, Yunzi Liu, Jin Ma, Jian Tan, L. Macia, C. Mackay, S. Chadban, Hui-ling Wu   +11 more
semanticscholar   +1 more source

Quality properties of various dietary fibers as isolated soy protein (ISP) replacements in pork emulsion systems

Journal of Animal Science and Technology, 2020
This study aimed to investigate the possibility of replacing the isolated soy protein (ISP) as a binding agent for wheat, oat, and bamboo shoot dietary fibers.
Sin-Young Park, Tae-Seok Oh, Gye-Woong Kim, Hack-Youn Kim   +3 more
doaj   +1 more source

B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids

Nature Communications, 2020
Short-chain fatty acids (SCFAs) butyrate and propionate are metabolites from dietary fiber's fermentation by gut microbiota that can affect differentiation or functions of T cells, macrophages and dendritic cells.
Helia Sanchez, Justin B. Moroney, Huoqun Gan, T. Shen, J. Im, Tianbao Li, Julia R. Taylor, H. Zan, P. Casali   +8 more
semanticscholar   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

The Change in Fiber Components of Caulerpa SP. Seaweeds (From Tual of Maluku) Due to Boiling Process [PDF]

, 2018
Caulerpasp. seaweeds are known as a source of fiber. The seaweeds are found on the coasts of Indonesia, such as Tual, Southeast Maluku. Caulerpa sp. is often consumed at fresh or boiled first by coastal communities.
Chrystiawan, R. (Rudy), Hidayat, T. (Taufik), Jacoeb, A. M. (Agoes), Nurjanah, N. (Nurjanah)   +3 more
core  

Role of Fibre in Nutritional Management of Pancreatic Diseases [PDF]

, 2019
The role of fibre intake in the management of patients with pancreatic disease is still controversial. In acute pancreatitis, a prebiotic enriched diet is associated with low rates of pancreatic necrosis infection, hospital stay, systemic inflammatory ...
Badiali, Danilo, Bruno, Giovanni, Ribichini, Emanuela, Rossi, Sara, Sacchi, MARIA CARLOTTA, Severi, Carola, Stigliano, Serena, Zaccari, Piera   +7 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The contribution of wheat to human diet and health [PDF]

, 2015
Wheat is the most important staple crop in temperate zones and is in increasing demand in countries undergoing urbanization and industrialization. In addition to being a major source of starch and energy, wheat also provides substantial amounts of a ...
Abrams, Abrams, Adom, Alam, Albani, Alsaffar, Anderson, Andersson, Andreasen, Antoine, Antoine, Asp, Avivi, Bacic, Badawy, Barron, Bates, Bates, Batifoulier, Beta, Birt, Blanco, Bonnin, Borrelli, Botticella, Bramley, Brown, Brownlee, Bruce, Buchanan, Bunzel, Buttriss, Cade, Capek, Carciofi, Carter, Chan, Chateigner-Boutin, Chiuve, Chung, Chung, Coleman, Coleman, Corol, Cummings, Cummings, Cummings, Demeke, Distelfeld, Distelfeld, Dornez, Du, Englyst, Feldman, Finney, Finnie, Fretzdorff, Gebruers, Gebruers, Gibson, Gibson, Gonzalez-Hernandez, Gopalan, Graham, Graybosch, Graybosch, Groos, Gujska, Hartings, Hasjim, Haska, Hazard, Henry, Hogg, Holasova, Hong, Huang, Hughes, Hughes, Humphreys, Hung, Huynh, Jende-Strid, Jensen, Jobling, Johnson, Joppa, Katz, Katz, Keaveney, Keenan, Khan, Khan, Kim, Kiribuchi-Otobe, Kroon, Lafiandra, Lafiandra, Lampi, Lawrence, Lazaridou, Lempereur, Li, Li, Li, Li, Likes, Lineback, Lobley, Loo, Lopez, Mandalari, Mares, Martinant, Mattila, McDermott, Mertz, Mesfin, Moore, Morell, Muir, Nakamura, Nakamura, Nemeth, Niculescu, Nilsson, Nurmi, Ohta, Olmos, Parker, Patterson, Pellny, Piironen, Piironen, Piironen, Piironen, Pomeranz, Price, Rahman, Rakszegi, Ranum, Rhodes, Rice, Ritsema, Roberfroid, Robertson, Robertson, Rodriguez-Mateos, Ross, Sampson, Saulnier, Saulnier, Saulnier, Schatzkin, Schirmer, Schmidt, Scholz-Ahrens, Sestili, Sharma, Shewry, Shewry, Shewry, Shewry, Shewry, Shewry, Shewry, Shimbata, Shoup, Simmonds, Slade, Slade, Smeds, Snape, Stone, Suzuki, Tako, Tester, Themeier, Theuwissen, Thompson, Tkachuk, Toepfer, Topping, Topping, Topping, Turner, Uauy, Uauy, Ueland, Vauzour, Vitaglione, Vogel, Ward, WHO, WHO, Worland, Yamamori, Yamamori, Yamamori, Yamamori, Yamamori, Zeisel, Zeisel, Zhou, Zhou   +204 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Pharmacokinetic modeling of cortisol binding to dietary fiber in the gastrointestinal tract [PDF]

, 2005
only availableCortisol is a glucocorticoid hormone produced in the adrenal cortex during stressful situations. The purpose of this project was to determine whether cortisol binds to dietary fiber and to design a pharmacokinetic model to predict whether ...
Arnett, Krista, Milanick, Mark A., Rosenwasser, Natalie   +2 more
core