Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Dietary Guidelines Post Kidney Transplant: Is This the Missing Link in Recovery and Graft Survival? [PDF]
Schneider S, Biggerstaff D, Barber TM.
europepmc +1 more source
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny +12 more
wiley +1 more source
Consumption and Greenhouse Gas Emissions Impacts of Population-Wide Adoption of Dietary Guidelines in China. [PDF]
Crowe S, Green R, Reynolds C, Shankar B.
europepmc +1 more source
A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies +3 more
wiley +1 more source
Diet quality of Chilean schoolchildren: How is it linked to adherence to dietary guidelines? [PDF]
Pinheiro Fernandes AC +4 more
europepmc +1 more source
DPSCs, hepatocytes, and exosomes were tested for liver fibrosis therapy. Exosome‐based treatment exhibited superior antioxidative and regenerative effects. Liver enzymes, oxidative stress, and profibrotic markers were significantly reduced. α‐SMA, desmin, and related gene expression were downregulated.
Sahar Rahimi +3 more
wiley +1 more source
Measuring Global Dietary Diversity by Considering Nutritional Functional Dissimilarity and Dietary Guidelines. [PDF]
Quan S, Zhu W.
europepmc +1 more source
Pulse consumption trends in the US in the context of 2025-30 Dietary Guidelines for Americans: analyses of NHANES data for 1999-2018. [PDF]
Drewnowski A +4 more
europepmc +1 more source

