Results 61 to 70 of about 2,469,952 (262)

Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity [PDF]

, 2011
Background Diets high in cereal-fiber (HCF) have been shown to improve whole-body insulin sensitivity. In search for potential mechanisms we hypothesized that a supplemented HCF-diet influences the composition of the human gut microbiota and/or ...
Pfeiffer, Andreas F. H., Arafat Ayman M, Leupelt Verena, Natalia Rudovich, Pfeiffer Andreas FH, Becker, Natalie, Verena Leupelt, Rudovich Natalia, Möhlig Matthias, Andreas FH Pfeiffer, Leupelt, Verena, Carl Alpert, Blaut Michael, Martin O Weickert, Arafat, Ayman M., Becker Natalie, Michael Blaut, Weickert Martin O, Weickert, Martin O., Möhlig, Matthias, Alpert, Carl, Rudovich, Natalia, Matthias Möhlig, Blaut, Michael, Natalie Becker, Alpert Carl, Ayman M Arafat   +26 more
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Dietary glycemic load and colorectal cancer risk

, 2001
Background: Insulin and insulin-like growth factors can stimulate proliferation of colorectal cells. High intake of refined carbohydrates and markers of insulin resistance are associated with colorectal cancer. To test the insulin/colon cancer hypothesis,
P. Boyle, S. Franceschi, L. Augustin, M. Parpinel, E. Negri, C. La Vecchia, L. Dal Maso, D.J. Jenkins, Parpinel M, La Vecchia C, Dal Maso L, Negri E, Franceschi S, Jenkins DJA, Boyle P, Parpinel, Maria, Augustin L   +16 more
core   +2 more sources

The Carnivore Connection Hypothesis: Revisited

Journal of Obesity, 2012
The “Carnivore Connection” hypothesizes that, during human evolution, a scarcity of dietary carbohydrate in diets with low plant : animal subsistence ratios led to insulin resistance providing a survival and reproductive advantage with selection of genes
Jennie C. Brand-Miller, Hayley J. Griffin, Stephen Colagiuri   +2 more
doaj   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Impact of Dietary Acid Load on Pancreatic β-cells Function and Insulin Resistance in Type 2 Diabetic Nigerians [PDF]

, 2022
Background: The possible impact of high intake of dietary acid on pancreatic β-cells dysfunction and insulin resistance in type 2 diabetic patients has been suggested from previous studies; but findings across different study groups are conflicting ...
Mohammed, Abdullahi, Ganiyu, Aliyu G.
core  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Higher dietary insulin index is directly associated with the odd of kidney stones

Scientific Reports
Kidney stones or Nephrolithiasis are the most common health condition associated with the urinary system. Dietary factors stand as important factors in the occurrence and development of kidney stones.
Niloofar Sadat Maddahi, Danial Fotros, Mohammad Hassan Sohouli, Hassan Mozaffari-Khosravi, Sayyed Saeid Khayyatzadeh   +4 more
doaj   +1 more source

Dietary glycemic index and dietary glycemic load is associated with apelin gene expression in visceral and subcutaneous adipose tissues of adults

Nutrition & Metabolism, 2019
Background Apelin, as an adipokine, plays an important role in the pathogenesis of insulin resistance and type 2 diabetes. This study aimed to determine whether the quality and quantity of dietary carbohydrates were associated with apelin gene expression
Emad Yuzbashian, Golaleh Asghari, Maryam Aghayan, Mehdi Hedayati, Maryam Zarkesh, Parvin Mirmiran, Alireza Khalaj   +6 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source