Results 71 to 80 of about 2,469,952 (262)

Association between dietary insulin index and load with brain derived neurotrophic factor, adropin and metabolic health status in Iranian adults

Scientific Reports, 2023
The associations of high potential insulinogenic foods with metabolic health (MH) status and brain-derived neurotrophic factor (BDNF) and adropin were not investigated quite enough.
Roxana Nematbakhsh, Zahra Hajhashemy, Keyhan Lotfi, Farnaz Shahdadian, Parisa Rouhani, Parvane Saneei   +5 more
doaj   +1 more source

Epidemiology of coronary heart disease in Asians in Britain [PDF]

, 1990
In countries where people of South Asian origin have settled, unexpectedly high coronary heart disease rates have been recorded in South Asian men and women compared with other ethnic groups. In England high CHD mortality is shared by Gujarati Hindus,
McKeigue, PM
core  

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Associations of insulin and insulin-like growth factors with physical performance in old age in the boyd orr and caerphilly studies. [PDF]

, 2012
OBJECTIVE: Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition.
David Gunnell, Gunnell, David, Gallacher, John, Martin, Richard M., Birnie, K, Gunnell, D, Kate Birnie, Gunnell David, Antony Bayer, Bayer Antony, John Gallacher, Ebrahim, S, Holly, Jeff MP, Bayer, A, Yoav Ben-Shlomo, Birnie Kate, Shah Ebrahim, Ben-Shlomo, Y, Ebrahim, Shah, Jeff M P Holly, Gunnell, DJ, Gallacher, J, Martin, Richard M, Holly, JM, Bayer, Antony, Jeff M. P. Holly, Martin Richard M., Martin, RM, Richard M Martin, Richard M. Martin, Holly Jeff M. P., Gallacher John, Holly, JMP, Holly, Jeff M. P., Bayer, Antony James, Birnie, Kate, Ben-Shlomo, Yoav, Ben-Shlomo Yoav, Ebrahim Shah, Gallacher, John Edward   +39 more
core   +3 more sources

Dysregulated insulin secretion is associated with pancreatic β‐cell hyperplasia and direct acinar‐β‐cell trans‐differentiation in partially eNOS‐deficient mice

Physiological Reports, 2022
eNOS‐deficient mice were previously shown to develop hypertension and metabolic alterations associated with insulin resistance either in standard dietary conditions (eNOS−/− homozygotes) or upon high‐fat diet (HFD) (eNOS+/− heterozygotes).
Michela Novelli, Matilde Masini, Cecilia Vecoli, Stefania Moscato, Niccola Funel, Anna Pippa, Letizia Mattii, Chiara Ippolito, Daniela Campani, Danilo Neglia, Pellegrino Masiello   +10 more
doaj   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Association of dietary glycemic and insulin index/load with odds of major depressive disorder: a case-control study

BMC Psychiatry
Background Dietary carbohydrate quality, reflected by glycemic index/load and insulin index/load, may influence brain function and mood through mechanisms such as glycemic fluctuations, oxidative stress, and inflammation.
Mahtab Karami Talandashti, Hossein Shahinfar, Mohammad Effatpanah, Jamileh Abolghasemi, Reyhaneh Morad Abbasi, Shima Jazayeri   +5 more
doaj   +1 more source

Reproducibility and relative validity of dietary glycaemic index and glycaemic load assessed by the food-frequency questionnaire used in the Dutch cohorts of the European prospective investigation into Cancer and Nutrition [PDF]

, 2009
Limited information is available on the reproducibility and validity of dietary glycaemic index (GI) and glycaemic load (GL) estimated by habitual diet assessment methods such as FFQ, including the FFQ used in the Dutch cohorts of the European ...
Ocke, M.C., A, A.D., van der, Feskens, E.J.M., Du, H., Verberne, L.D.M., Bakel, M., van   +5 more
core   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

Advanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo, Nuria Matesanz, Jorge‐Luis Torres, Alba C. Arcones, Juan Ignacio Jiménez‐Loygorri, Alfonso Mora, Leticia Herrera‐Melle, Luis Leiva‐Vega, Maria Elena Rodriguez, Lourdes Hernández‐Cosido, Marta Leon, Paula Yong González, Teresa Durán, Tamara Parracho, Francisca Mulero, Rubén Nogueiras, J. Simon C. Arthur, Angel R. Nebreda, Roger J. Davis, Miguel Marcos, Guadalupe Sabio   +20 more
wiley   +1 more source

The effect of a low renal acid load diet on blood pressure, lipid profile, and blood glucose indices in patients with type 2 diabetes: a randomized clinical trial

Nutrition Journal, 2023
Background Observational studies have reported that dietary renal acid load has an important role in insulin resistance and metabolic factors. The aim of the present study was to assess the effect of a low renal acid load diet (LRALD) on blood pressure ...
Maryam Armin, Zahra Heidari, Gholamreza Askari, Bijan Iraj, Cain C. T. Clark, Mohammad Hossein Rouhani   +5 more
doaj   +1 more source