Results 111 to 120 of about 321,144 (295)

Engineering chitosan nanoparticles for targeted doxorubicin delivery in liver cancer: A mechanistic and preclinical review

Carbohydrate Polymer Technologies and Applications
Hepatocellular carcinoma (HCC) remains a major global health burden, characterized by poor prognosis, limited treatment options, and high chemoresistance.
Jianfei Sun, Huiying Yu, Bita Badehnoosh
doaj   +1 more source

Fortification and health: challenges and opportunities. [PDF]

, 2015
Fortification is the process of adding nutrients or non-nutrient bioactive components to edible products (e.g., food, food constituents, or supplements). Fortification can be used to correct or prevent widespread nutrient intake shortfalls and associated
Bailey, Regan L, Dary, Omar, Dwyer, Johanna T, Gaine, P Courtney, Jarvis, Ashley B, Keen, Carl L, King, Janet C, Miller, Kevin B, Philbert, Martin A, Tarasuk, Valerie, Taylor, Christine L, Wiemer, Kathryn L   +11 more
core  

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Dietary Patterns of U.S. Older Adults and Their Associations with Diet Quality, Health, and Food Insecurity

Public Health Nutrition
Objective: Identify dietary patterns among U.S. older adults and examine their associations with sociodemographic and health characteristics including economic and physical-functioning-related food insecurity.
Anniebelle J. Sassine, Edwina A. Wambogo, Alanna J. Moshfegh, Nadine R. Sahyoun   +3 more
doaj   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

MicroRNA-1303 in cancer pathogenesis and therapy: clinical implications for biomarker development and targeted treatment strategies

Cancer Cell International
Cancer remains one of the most formidable global health challenges due to its complex pathogenesis, late-stage diagnosis, and limited therapeutic options for many subtypes.
Lingzi Zheng, Ling Hu, Bita Badehnoosh
doaj   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Short-term effects of a synbiotic diet on thyroid and sex hormones in Sarabi Dogs

BMC Veterinary Research
Background Synbiotic products are those Functional foods/feeds that contain both probiotic and prebiotic strains and have health-promoting effects beyond probiotics or prebiotics alone.
Ali Khatami, Hadi Pourjafar, Mehrdad Neshat Gharamaleki   +2 more
doaj   +1 more source

Formulation optimization of a sucrose-free probiotic dark chocolate; rheological characteristics and viability of Saccharomyces boulardi

Current Research in Food Science
The use of polyols as sucrose-replacer in chocolate formulation has increased in the last years because of the high occurrence of the metabolic syndrome.
Haniyeh Rasouli Pirouzian, Hadi Pourjafar, Fereshteh Ansari, Nezam Armand, Seid Mahdi Jafari   +4 more
doaj   +1 more source