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Diethylcarbamazine disposition in patients with onchocerciasis
Clinical Pharmacology and Therapeutics, 1981Diethylcarbamazine (DEC), 0.5 mg/kg, was taken orally by six patients being treated for onchocerciasis. Blood samples were taken at timed intervals for 48 hr and urine and feces collected for 4 days. Plasma and urinary concentrations of DEC and DEC N-oxide were measured by gas-liquid chromatography.
G, Edwards +5 more
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Analysis of diethylcarbamazine and diethylcarbamazine-N-oxide by gas chromatography
Archives of Pharmacal Research, 1996Diethylcarbamazine (DEC, 1-diethylcarbamyl-4-methylpiperazine) is an antiparasitic piperazine derivative used in the treatment of lymphatic filariasis caused byWuchereria bancrofti, Brugia malayi orBrugia timori. DEC-N-oxide is a major metabolite in humans and has antifilarial activity.
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Availability of diethylcarbamazine citrate
American Journal of Health-System Pharmacy, 1986L, Sklaver, C, Murray
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Diethylcarbamazine in ascariasis
The Indian Journal of Pediatrics, 1953N. G. Mojumdar, B. Biswas
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PROTEINURIA ASSOCIATED WITH DIETHYLCARBAMAZINE
The Lancet, 1980J L, Ngu, A, Mate, R, Leke, V, Titanji
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