Results 121 to 130 of about 336,140 (171)
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Diethylcarbamazine in the treatment of onchocerciasis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1953Abstract 1. (1) Eleven patients suffering from onchocerciasis were treated with diethylcarbamazine. 2. (2) The standard course of treatment was 6 mg. drug per kg. patient's body weight given daily (in three equal doses) for 7 days, followed by 9 mg. per kg. for 14 days. 3.
J C, ADAMS, A W, WOODRUFF
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Onchocerciasis treated with diethylcarbamazine
British Journal of Dermatology, 1977One hundred patients with onchocerciasis were treated with diethylcarbamazine: a single course of treatment led to clinical cure in 48% of the patients; no means of anticipating which patients might require only a single course of treatment was found.
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Identification and quantification of diethylcarbamazine and diethylcarbamazineN-oxide in rat urine
Xenobiotica, 19811. Diethylcarbamazine and its major metabolite, diethylcarbamazine N-oxide have been identified and quantified in the urine of rats dosed orally with [14C]diethylcarbamazine citrate.2. The urinary excretion of diethylcarbamazine N-oxide as percentage of dose was not dose-dependent.3. These observations are in agreement with previous studies.
G, Edwards +3 more
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Diethylcarbamazine (Hetrazan) in Experimental Trichinosis
The American Journal of Tropical Medicine and Hygiene, 1952The general acceptance of diethylcarbamazine or Hetrazan (1-diethylcarbamyl-4-methylpiperazine hydrochloride [or dihydrogen citrate]) as a useful drug in the treatment of filarial diseases caused by several types of worm and affecting various animals, including man, has stimulated its trial in treatment of other nematode infections. It has been claimed
T B, MAGATH, J H, THOMPSON
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Diethylcarbamazine disposition in patients with onchocerciasis
Clinical Pharmacology and Therapeutics, 1981Diethylcarbamazine (DEC), 0.5 mg/kg, was taken orally by six patients being treated for onchocerciasis. Blood samples were taken at timed intervals for 48 hr and urine and feces collected for 4 days. Plasma and urinary concentrations of DEC and DEC N-oxide were measured by gas-liquid chromatography.
G, Edwards +5 more
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Analysis of diethylcarbamazine and diethylcarbamazine-N-oxide by gas chromatography
Archives of Pharmacal Research, 1996Diethylcarbamazine (DEC, 1-diethylcarbamyl-4-methylpiperazine) is an antiparasitic piperazine derivative used in the treatment of lymphatic filariasis caused byWuchereria bancrofti, Brugia malayi orBrugia timori. DEC-N-oxide is a major metabolite in humans and has antifilarial activity.
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Availability of diethylcarbamazine citrate
American Journal of Health-System Pharmacy, 1986L, Sklaver, C, Murray
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Diethylcarbamazine in ascariasis
The Indian Journal of Pediatrics, 1953N. G. Mojumdar, B. Biswas
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