Results 31 to 40 of about 367,858 (219)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Factors affecting fruit and vegetable consumption and purchase behavior of adults in sub-Saharan Africa: A rapid review

Frontiers in Nutrition, 2023
In order to achieve the Sustainable Development Goals, considerable dietary shifts, including an increase in the consumption of fruit and vegetables (FV) will be required.
Barbara Stadlmayr, Barbara Stadlmayr, Ursula Trübswasser, Stepha McMullin, Alice Karanja, Maria Wurzinger, Laura Hundscheid, Petra Riefler, Stefanie Lemke, Stefanie Lemke, Inge D. Brouwer, Isolde Sommer   +11 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A systematic scoping review of urban food environment research, interventions, and measurement approaches in eight low- and middle-income countries

International Journal of Behavioral Nutrition and Physical Activity
Background Food environments in low- and middle-income countries (LMICs) are undergoing rapid transformation, particularly in urban and peri-urban settings.
Amy Margolies, Dorcas Amunga, Esther M. Choo   +2 more
doaj   +1 more source

Current and potential contributions of large-scale food fortification to meeting micronutrient requirements in Senegal: a modelling study using household food consumption data

BMJ Public Health
Introduction Micronutrient deficiencies are common among women of reproductive age (WRA) and children in Senegal. Large-scale food fortification (LSFF) can help fill gaps in dietary intake.Methods We used household food consumption data to model the ...
Katherine P Adams, Reina Engle-Stone, Brent Wibberley, Becky L Tsang, Ann Tarini, Maguette Beye, Laura A Rowe   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Methodological considerations and cost to measure coverage of multisectoral nutrition interventions: protocol for the One Nutrition Coverage Survey in Bangladesh

BMJ Open
Introduction Despite global commitments to eliminate malnutrition, over half the world’s population remains affected. Multisectoral nutrition interventions targeting both proximate and distal causes of malnutrition are essential across the lifespan. Yet,
Phuong Hong Nguyen, Rebecca Heidkamp, Melinda Kay Munos, Archis Banerjee, Swetha Manohar, Sumanta Neupane, Niharika Pandya, Sunny S Kim   +7 more
doaj   +1 more source

Preclinical models of atherosclerosis: An overview [PDF]

Iranian Journal of Basic Medical Sciences
Atherosclerosis is a primary cause of illness and death globally and its mechanism is still unclear. Different animal models have been created to evaluate the progression of atherosclerosis, allowing researchers to carefully control the circumstances of ...
Priyanka Arya, Vikram Sharma, Surabhi Thapliyal, Rahul Sagar, Priyanka Singh   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Toilet construction under the Swachh Bharat Mission and infant mortality in India

Scientific Reports
Improvement of water and sanitation conditions may reduce infant mortality, particularly in countries like India where open defecation is highly prevalent.
Suman Chakrabarti, Soyra Gune, Tim A. Bruckner, Julie Strominger, Parvati Singh   +4 more
doaj   +1 more source