Results 71 to 80 of about 1,958,924 (310)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Journal of Mechanism and Institution Design, 2020 We consider n-person pure bargaining games in which the space of feasible payoffs is constructed via a normal form differential game. At the beginning of the game the agents bargain over strategies to be played over an infinite time horizon. An initial
Simon Hoof
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Differential games through viability theory : old and recent results. [PDF]
This article is devoted to a survey of results for differential games obtained through Viability Theory. We recall the basic theory for differential games (obtained in the 1990s), but we also give an overview of recent advances in the following areas ...
Saint-Pierre, Patrick +2 more
core
IDP-Core: Novel Cooperative Solution for Differential Games
Mathematics, 2020 IDP-core is a new cooperative solution for dynamic and differential games. A novel approach of constructing solutions for dynamic and differential games was employed in which the time consistency property was used as the main axiom property for the ...
Ovanes Petrosian, Victor Zakharov
doaj +1 more source
Journal of Mathematical Analysis and Applications, 1991 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +4 more sources
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Necessary and Sufficient Conditions for Pareto Optimality in Infinite Horizon Cooperative Differential Games [PDF]
In this article we derive necessary and sufficient conditions for the existence of Pareto optimal solutions for infinite horizon cooperative differential games. We consider games defined by non autonomous and discounted autonomous systems.
Engwerda, J.C., Reddy, P.V.
core
On the Effect of the Absorption Coefficient in a Differential Game of Pollution Control
Mathematics, 2020 We consider various approaches for a characteristic function construction on the example of an n players differential game of pollution control with a prescribed duration.
Ekaterina Marova +3 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source